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Compare Lantus vs. Actos

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Lantus (insulin glargine) and Actos (pioglitazone) are both used to manage diabetes, but they work in different ways and are used for different types of diabetes. Lantus is a long-acting insulin injected under the skin, typically once daily, to help control blood sugar levels in both Type 1 and Type 2 diabetes. In contrast, Actos is an oral medication taken once daily that helps your body use insulin more effectively, but it is only used for Type 2 diabetes. Lantus can cause low blood sugar levels and weight gain, while Actos may take several weeks to show its full effect and can cause fluid build-up, weight gain, and increased risk of bladder cancer and bone fractures. Additionally, Actos is not suitable for people with heart failure or bladder cancer, whereas Lantus requires careful monitoring to avoid dangerously low blood sugar levels. Both medications require a prescription and have specific storage and usage instructions to ensure they work effectively.

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