Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Lantus (insulin glargine) and Actos (pioglitazone) are both used to manage diabetes, but they work in different ways and are used for different types of diabetes. Lantus is a long-acting insulin injected under the skin, typically once daily, to help control blood sugar levels in both Type 1 and Type 2 diabetes. In contrast, Actos is an oral medication taken once daily that helps your body use insulin more effectively, but it is only used for Type 2 diabetes. Lantus can cause low blood sugar levels and weight gain, while Actos may take several weeks to show its full effect and can cause fluid build-up, weight gain, and increased risk of bladder cancer and bone fractures. Additionally, Actos is not suitable for people with heart failure or bladder cancer, whereas Lantus requires careful monitoring to avoid dangerously low blood sugar levels. Both medications require a prescription and have specific storage and usage instructions to ensure they work effectively.
Lantus (insulin glargine)
Pioglitazone (Actos)
Lantus (insulin glargine)
Pioglitazone (Actos)
Summary of Lantus vs. Actos
Summary for Insulin
Prescription only
Lantus (insulin glargine) is a type of long-acting insulin. It's used to help manage blood sugar levels in people with Type 1 diabetes or Type 2 diabetes. Lantus (insulin glargine) is injected under the skin once daily. Your dose will depend on a few things, such as the type of diabetes you have and your blood sugar levels. This medication comes in a vial (Lantus) as well as in a prefilled insulin pen (Lantus Solostar). Some side effects include upper respiratory tract infections. It can also cause redness and swelling at the injection site.
Summary for Thiazolidinedione
Prescription only
Pioglitazone (Actos) is an oral medication used to treat Type 2 diabetes in adults, along with diet and exercise. It's a thiazolidinedione, which works by helping your body respond better to insulin. This medication is taken by mouth once a day and is available in both brand and generic forms. Side effects include headache, swelling in the body, and weight gain. There's also a serious warning that it can cause or worsen heart failure.