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Compare Prandin vs. Lantus

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Repaglinide
Lantus (insulin glargine)
Repaglinide
Lantus (insulin glargine)
Summary of Prandin vs. Lantus
Summary for Glinide
Prescription only
Repaglinide is an oral tablet taken in addition to diet and exercise to control blood sugar in adults with Type 2 diabetes. It belongs to the drug class called meglitinide, and works similar to sulfonylureas. The usual dosing is to take 0.5 mg to 4 mg by mouth before each meal. Potential warnings and side effects include low blood sugar, headache, and diarrhea. The brand name Prandin has been discontinued, but this medication is still available as a generic.
Summary for Insulin
Prescription only
Lantus (insulin glargine) is a long-acting insulin. It's used to manage blood sugar levels in adults and children with Type 1 diabetes or Type 2 diabetes. Lantus (insulin glargine) is injected under the skin, typically once daily or as directed by your healthcare team. Your care team will determine your dose of Lantus (insulin glargine) based on different factors, such as your diet and blood sugar levels. Lantus (insulin glargine) comes as a vial and a prefilled insulin pen (Lantus Solostar). Some side effects of this medication include redness and swelling at the injection site, and upper respiratory tract infections.
Indications of Prandin vs. Lantus
Indications for

•Type 2 diabetes

Indications for

•Type 1 diabetes (T1D)

•Type 2 diabetes (T2D)
Pros and Cons of Prandin vs. Lantus
Pros and Const for Glinide
Pros

•Can quickly lower blood sugar during meal times

•Comes as an oral tablet taken by mouth

•Available as a lower-cost generic

Cons

•Has a risk of low blood sugar

•Can cause some weight gain

•Can interact with many medications

Pros and Const for Insulin
Pros

•Can control your blood sugar levels for about 24 hours

•Typically injected once daily

•Approved for children and adults

•Available as a vial and pre-filled pen

Cons

•Given as an injection

•Raises risk of dangerously low blood sugar levels

•Might cause weight gain

•Can't be mixed with other insulins within the same syringe
Common Side Effects of Prandin vs. Lantus
Common Side Effects for

•Low blood sugar (31%)

•Upper respiratory infection (16%)

•Headache (11%)

•Sinus infection (6%)

•Joint pain (6%)

•Nausea (5%)

•Diarrhea (5%)

•Back pain (5%)

Common Side Effects for
Type 2 diabetes (T2D)

•Upper respiratory tract infection (up to 29%)

•Swelling in the hands or feet (20%)

•High blood pressure (20%)

•Flu, sinus infections, or bronchitis (up to 19%)

•Cataract (15%)

•Joint pain (14%)

•Pain in the hands and feet (13%)

•Back pain (13%)

•Cough (12%)

•Urinary tract infection (11%)

•Diarrhea (11%)

•Depression (11%)

•Headache (10%)

Note: People with T1D typically experienced less side effects than people with T2D, but are at higher risk for hypoglycemia.
Warnings of Prandin vs. Lantus
Common Side Effects for

•Low blood sugar

•Possible risk of serious heart problems

Common Side Effects for

•Risk of serious infections

•Risk of high and low blood sugar levels

•Dangerously low blood sugar levels (hypoglycemia)

•Low blood potassium levels

•Swelling and heart failure

•Severe allergic reactions
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Compare Prandin vs. Lantus

Summary of Prandin vs. Lantus

Indications of Prandin vs. Lantus

Pros and Cons of Prandin vs. Lantus

Common Side Effects of Prandin vs. Lantus

Warnings of Prandin vs. Lantus

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