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Compare Prandin vs. Lantus

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Repaglinide and Lantus (insulin glargine) are both medications used to manage blood sugar levels in people with diabetes. Repaglinide is specifically used for Type 2 diabetes, while Lantus is used for both Type 1 and Type 2 diabetes. Repaglinide is taken before meals to stimulate the pancreas to release insulin. In contrast, Lantus is a long-acting insulin injected under the skin once daily to help control blood sugar levels throughout the day. Repaglinide is available as a generic, while Lantus is available as a brand-name medication and lower-cost generic and comes in a vial or prefilled pen. Common side effects of repaglinide include low blood sugar, headache, and diarrhea, whereas Lantus can cause injection site reactions, upper respiratory infections, and low blood sugar. It's best to avoid alcohol with both medications, because drinking alcohol can increase the risk of low blood sugar.

  • Repaglinide
    Lantus (insulin glargine)
  • Repaglinide
    Lantus (insulin glargine)

  • Summary of Prandin vs. Lantus

    Summary for Glinide
    Prescription only

    Repaglinide is an oral tablet taken in addition to diet and exercise to control blood sugar in adults with Type 2 diabetes. It belongs to the drug class called meglitinide, and works similar to sulfonylureas. The usual dosing is to take 0.5 mg to 4 mg by mouth before each meal. Potential warnings and side effects include low blood sugar, headache, and diarrhea. The brand name Prandin has been discontinued, but this medication is still available as a generic.

    Summary for Insulin
    Prescription only

    Lantus (insulin glargine) is a type of long-acting insulin. It's used to help manage blood sugar levels in people with Type 1 diabetes or Type 2 diabetes. Lantus (insulin glargine) is injected under the skin once daily. Your dose will depend on a few things, such as the type of diabetes you have and your blood sugar levels. This medication comes in a vial (Lantus) as well as in a prefilled insulin pen (Lantus Solostar). Some side effects include upper respiratory tract infections. It can also cause redness and swelling at the injection site.

  • Indications of Prandin vs. Lantus

    Indications for
    •Type 2 diabetes
    Indications for
    •Type 1 diabetes (T1D)
    •Type 2 diabetes (T2D)

  • Pros and Cons of Prandin vs. Lantus

    Pros and Const for Glinide
    Pros
    •Can quickly lower blood sugar during meal times
    •Comes as an oral tablet taken by mouth
    •Available as a lower-cost generic
    Cons
    •Has a risk of low blood sugar
    •Can cause some weight gain
    •Can interact with many medications
    Pros and Const for Insulin
    Pros
    •Helps keep your blood sugar controlled for about 24 hours
    •Injected once daily
    •Approved for both adults and children
    •Available as a vial and prefilled pen
    Cons
    •Given as an injection under the skin
    •Has a risk of causing dangerously low blood sugar
    •Might cause weight gain
    •Can't be mixed with other insulins within the same syringe

  • Common Side Effects of Prandin vs. Lantus

    Common Side Effects for
    •Low blood sugar (31%)
    •Upper respiratory infection (16%)
    •Headache (11%)
    •Sinus infection (6%)
    •Joint pain (6%)
    •Nausea (5%)
    •Diarrhea (5%)
    •Back pain (5%)
    Common Side Effects for

    Type 1 diabetes

    •Upper respiratory tract infection (22%)
    •Other infection (9%)
    •Accidental injury (6%)
    •Headache (6%)

    Type 2 diabetes

    •Upper respiratory tract infection (11%)
    •Other infection (10%)
    •Eye problem (6%)

  • Warnings of Prandin vs. Lantus

    Common Side Effects for
    •Low blood sugar
    •Possible risk of serious heart problems
    Common Side Effects for
    •Risk of infection from sharing pens and needles
    •Risk of changes to blood sugar levels with changes to your insulin routine
    •Low blood sugar (hypoglycemia)
    •Low potassium levels
    •Swelling and risk of heart failure when using with certain diabetes medications
    •Severe allergic reaction

  • Prices with our coupons for Prandin vs. Lantus

    Learn more about Repaglinide
    Learn more about Lantus

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