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Compare Prandin vs. Starlix

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Repaglinide and nateglinide are both oral prescription medications used to help control blood sugar in people with Type 2 diabetes. They belong to the same drug class and work by stimulating your pancreas release more insulin. However, there are some differences between them. Repaglinide is typically taken 0.5 mg to 4 mg before each meal, while the typical dose of nateglinide is 120 mg three times a day before meals. Both medications are only available as a lower-cost generic. Both medications can also cause low blood sugar and weight gain and interact with many other medications. Be sure your prescriber and pharmacist have a complete list of your medications.

  • Repaglinide
    Nateglinide
  • Repaglinide
    Nateglinide

  • Summary of Prandin vs. Starlix

    Summary for Glinide
    Prescription only

    Repaglinide is an oral tablet taken in addition to diet and exercise to control blood sugar in adults with Type 2 diabetes. It belongs to the drug class called meglitinide, and works similar to sulfonylureas. The usual dosing is to take 0.5 mg to 4 mg by mouth before each meal. Potential warnings and side effects include low blood sugar, headache, and diarrhea. The brand name Prandin has been discontinued, but this medication is still available as a generic.

    Summary for Meglitinide
    Prescription only

    Nateglinide is an add-on medication to diet and exercise to control blood sugar in people with Type 2 diabetes. This medication comes as a tablet that's taken by mouth. It must be taken three times a day, which might be inconvenient for some people.

  • Indications of Prandin vs. Starlix

    Indications for
    •Type 2 diabetes
    Indications for
    •Type 2 diabetes

  • Pros and Cons of Prandin vs. Starlix

    Pros and Const for Glinide
    Pros
    •Can quickly lower blood sugar during meal times
    •Comes as an oral tablet taken by mouth
    •Available as a lower-cost generic
    Cons
    •Has a risk of low blood sugar
    •Can cause some weight gain
    •Can interact with many medications
    Pros and Const for Meglitinide
    Pros
    •Helps release insulin into the body within 20 minutes of taking
    •Lowers A1C levels by around 0.75%
    •Good option if you can't take metformin because of side effects or poor kidney function
    •Lower-cost generic available
    Cons
    •Need to take 1 to 30 minutes before each meal
    •Must take 3 times a day, which can be inconvenient
    •Might be more likely to cause weight gain than other diabetes medications
    •Not for people with Type 1 diabetes

  • Common Side Effects of Prandin vs. Starlix

    Common Side Effects for
    •Low blood sugar (31%)
    •Upper respiratory infection (16%)
    •Headache (11%)
    •Sinus infection (6%)
    •Joint pain (6%)
    •Nausea (5%)
    •Diarrhea (5%)
    •Back pain (5%)
    Common Side Effects for
    •Upper respiratory tract infection (11%)
    •Back pain (4%)
    •Flu symptoms (4%)
    •Dizziness (4%)
    •Joint problems (3%)
    •Diarrhea (3%)
    •Accidental trauma (3%)
    •Bronchitis (3%)

  • Warnings of Prandin vs. Starlix

    Common Side Effects for
    •Low blood sugar
    •Possible risk of serious heart problems
    Common Side Effects for
    •Low blood sugar (hypoglycemia)

  • Prices with our coupons for Prandin vs. Starlix

    Learn more about Repaglinide
    Learn more about Nateglinide

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