Key takeaways
Repaglinide and nateglinide are both oral prescription medications used to help control blood sugar in people with Type 2 diabetes. They belong to the same drug class and work by stimulating your pancreas release more insulin. However, there are some differences between them. Repaglinide is typically taken 0.5 mg to 4 mg before each meal, while the typical dose of nateglinide is 120 mg three times a day before meals. Both medications are only available as a lower-cost generic. Both medications can also cause low blood sugar and weight gain and interact with many other medications. Be sure your prescriber and pharmacist have a complete list of your medications.
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