Compare Toujeo vs. Janumet

Toujeo (insulin glargine) and Janumet (sitagliptin/metformin) are both used to manage diabetes, but they have some key differences. Toujeo is a long-acting insulin injected once daily to help control blood sugar in both Type 1 and Type 2 diabetes. It's available only as a brand-name medication and comes in prefilled pens. Toujeo lowers blood sugar by helping your body absorb sugar from the bloodstream and store it for energy. On the other hand, Janumet is an oral medication combining sitagliptin, a DPP-4 inhibitor, and metformin, a biguanide. It's used specifically for Type 2 diabetes. Janumet helps control blood sugar by improving insulin function and reducing sugar production in the liver. Unlike Toujeo, Janumet is taken with meals and is available in both immediate-release and extended-release forms. While Toujeo can cause weight gain and low blood sugar, Janumet is less likely to cause these issues but can lead to side effects like diarrhea and upper respiratory infections. Additionally, Janumet is not suitable for people with severe kidney problems, whereas Toujeo requires careful monitoring to avoid low blood sugar and other complications.