Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Levemir (insulin detemir) and Toujeo (insulin glargine) are both long-acting insulins used to manage diabetes, but they have some key differences. Levemir can be injected once or twice daily, while Toujeo is typically injected once daily. Toujeo is an ultra-long-acting insulin that lasts up to 36 hours, whereas Levemir lasts up to 24 hours. Toujeo is more concentrated, containing 300 units/mL of insulin glargine, making it suitable for those needing higher doses, while Levemir does not have this higher concentration option. Levemir is available in vials and FlexPens, but Toujeo only comes in prefilled pens. Levemir Flexpens has been discontinued as of April 2024, and vials will be discontinued by December 2024, whereas Toujeo is only available as a brand. Both medications can cause low blood sugar and should not be mixed with other insulins within the same syringes.
Levemir (insulin detemir)
Toujeo (insulin glargine)
Levemir (insulin detemir)
Toujeo (insulin glargine)
Summary of Levemir vs. Toujeo
Summary for Insulin
Prescription only
Levemir (insulin detemir) is a long-acting insulin that helps control high blood sugar levels in children and adults. It's injected under the skin, typically once or twice daily. Like all insulins, Levemir (insulin detemir) can raise your risk for low blood sugar, so make sure to keep fast-acting sugars with you in case your blood sugar level drops too low. This medication comes in vials. But it's also available as a Flexpen for people who have trouble drawing up insulin from the vial.
Summary for Insulin
Prescription only
Toujeo SoloStar and Toujeo Max SoloStar are a pair of brand names for insulin glargine. This medication is a long-acting insulin that's used for diabetes in adults and children. It's a more concentrated version of insulin glargine containing 300 units/mL. It comes as prefilled pens that you use for once-daily injections under the skin. Side effects include common cold symptoms and low blood sugar.
•Long-lasting insulin that provides consistent, all-day blood sugar control
•Given once a day
•Available as a prefilled pen
•Good choice for people who need high doses of long-acting insulin
•Can use in children as young as 6 years old
Cons
•Must inject the medication under the skin
•Might be difficult for some people to administer correctly
•Can cause weight gain and low blood sugar (hypoglycemia)
•Can't be mixed with other insulins
Common Side Effects of Levemir vs. Toujeo
Common Side Effects for
•Shakiness, hunger, and other symptoms of low blood sugar (up to 93%, depending on what other blood sugar medications you're taking)
•Common cold involving the nose, throat, and lungs (up to 27%)
•Headache (up to 23%)
•Pain or irritation of the throat (10%)
•Back pain (8%)
•Fever, chills, and other flu-like symptoms (up to 8%)
•Stomach pain (6%)
Please note: These side effects were reported by people who took Levemir (insulin detemir) for type 1 diabetes. Your risk for side effects might be different if you have type 2 diabetes.
Common Side Effects for
•Low blood sugar
•Common cold symptoms
•Infection involving the nose, throat, and lungs
Warnings of Levemir vs. Toujeo
Common Side Effects for
•Infections
•Low blood sugar
•Severe allergic reactions
•Low blood potassium levels
•Swelling from fluids and risk of heart failure
Common Side Effects for
•Risk of infections with pen sharing
•Low blood sugar (hypoglycemia)
•Low blood potassium levels
•Swelling and heart failure when used with certain diabetes medications