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Compare Toujeo vs. Januvia

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Toujeo (insulin glargine) and Januvia (sitagliptin) are both used to manage diabetes, but they have some key differences. Toujeo is a long-acting insulin used for both Type 1 and Type 2 diabetes. It's injected under the skin once daily. Toujeo helps your body absorb sugar from the bloodstream and store it for energy. On the other hand, Januvia is a DPP-4 inhibitor taken orally once a day, and is only used for Type 2 diabetes. Januvia works by blocking a protein that breaks down hormones, allowing insulin to stay in your body longer and reducing sugar production. While Toujeo can cause low blood sugar and weight gain, Januvia is not known to affect body weight but can cause severe joint pain and kidney problems. Additionally, Toujeo is available only as a brand-name medication, whereas Januvia also has a combination form with metformin called Janumet.

  • Toujeo (insulin glargine)
    Januvia (sitagliptin)
  • Toujeo (insulin glargine)
    Januvia (sitagliptin)

  • Summary of Toujeo vs. Januvia

    Summary for Insulin
    Prescription only

    Toujeo SoloStar and Toujeo Max SoloStar are a pair of brand names for insulin glargine. This medication is a long-acting insulin that's used for diabetes in adults and children. It's a more concentrated version of insulin glargine containing 300 units/mL. It comes as prefilled pens that you use for once-daily injections under the skin. Side effects include common cold symptoms and low blood sugar.

    Summary for DDP-4 inhibitor
    Prescription only

    Januvia (sitagliptin) is a prescription medication used along with a healthy diet and exercise to treat Type 2 diabetes. It belongs to the drug class dipeptidyl peptidase-4 (DPP-4) inhibitor, also known as gliptins. Januvia (sitagliptin) is taken by mouth, typically once daily. Most people don't experience many side effects from this medication, but possible ones include stuffy or runny nose, sore throat, and headache.

  • Indications of Toujeo vs. Januvia

    Indications for
    •Type 1 diabetes
    •Type 2 diabetes
    Indications for
    •Type 2 diabetes in adults

  • Pros and Cons of Toujeo vs. Januvia

    Pros and Const for Insulin
    Pros
    •Long-lasting insulin that provides consistent, all-day blood sugar control
    •Given once a day
    •Available as a prefilled pen
    •Good choice for people who need high doses of long-acting insulin
    •Can use in children as young as 6 years old
    Cons
    •Must inject the medication under the skin
    •Might be difficult for some people to administer correctly
    •Can cause weight gain and low blood sugar (hypoglycemia)
    •Can't be mixed with other insulins
    Pros and Const for DDP-4 inhibitor
    Pros
    •Only taken once a day
    •Can take with or without food
    •Not known to affect your body weight
    Cons
    •Can cause severe joint pain
    •Not a first choice option for people with Type 2 diabetes and heart problems
    •Might cause sudden kidney injury in people with kidney problems

  • Common Side Effects of Toujeo vs. Januvia

    Common Side Effects for
    •Low blood sugar
    •Common cold symptoms
    •Infection involving the nose, throat, and lungs
    Common Side Effects for
    •Runny nose, sore throat, and other symptoms of the common cold (5%)

  • Warnings of Toujeo vs. Januvia

    Common Side Effects for
    •Risk of infections with pen sharing
    •Low blood sugar (hypoglycemia)
    •Low blood potassium levels
    •Swelling and heart failure when used with certain diabetes medications
    •Allergic reactions
    Common Side Effects for
    •Pancreas problems
    •Heart failure
    •Sudden kidney problems
    •Serious allergic reactions
    •Joint pain
    •Severe skin reactions

  • Prices with our coupons for Toujeo vs. Januvia

    Learn more about Toujeo
    Learn more about Januvia

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