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Compare Toujeo vs. Glyburide

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Toujeo (insulin glargine) and glyburide (Glynase) are both used to manage diabetes, but they have some key differences. Toujeo is a long-acting insulin injected once daily to help control blood sugar levels in both Type 1 and Type 2 diabetes. It's available only as a brand-name medication and comes in prefilled pens. Toujeo works by helping your body absorb sugar from the bloodstream and store it for energy. Glyburide, on the other hand, is an oral medication that's typically taken once or twice daily and is used specifically for Type 2 diabetes. It belongs to the sulfonylurea class and works by stimulating the pancreas to release more insulin. Glyburide is available in both generic and brand-name forms. While Toujeo can cause low blood sugar and weight gain, glyburide also carries a risk of low blood sugar and may cause heartburn and nausea. Additionally, glyburide is not suitable for people with Type 1 diabetes or those experiencing diabetic ketoacidosis.

  • Toujeo (insulin glargine)
    Glyburide
  • Toujeo (insulin glargine)
    Glyburide

  • Summary of Toujeo vs. Glyburide

    Summary for Insulin
    Prescription only

    Toujeo SoloStar and Toujeo Max SoloStar are a pair of brand names for insulin glargine. This medication is a long-acting insulin that's used for diabetes in adults and children. It's a more concentrated version of insulin glargine containing 300 units/mL. It comes as prefilled pens that you use for once-daily injections under the skin. Side effects include common cold symptoms and low blood sugar.

    Summary for Sulfonylurea
    Prescription only

    Glyburide is taken by mouth to lower blood sugar levels for people who have Type 2 diabetes. This medication isn't meant to be taken alone, but in addition to eating a healthy diet and engaging in regular exercise. Glyburide is typically taken once or twice daily, depending on your dose.

  • Indications of Toujeo vs. Glyburide

    Indications for
    •Type 1 diabetes
    •Type 2 diabetes
    Indications for
    •Type 2 diabetes

  • Pros and Cons of Toujeo vs. Glyburide

    Pros and Const for Insulin
    Pros
    •Long-lasting insulin that provides consistent, all-day blood sugar control
    •Given once a day
    •Available as a prefilled pen
    •Good choice for people who need high doses of long-acting insulin
    •Can use in children as young as 6 years old
    Cons
    •Must inject the medication under the skin
    •Might be difficult for some people to administer correctly
    •Can cause weight gain and low blood sugar (hypoglycemia)
    •Can't be mixed with other insulins
    Pros and Const for Sulfonylurea
    Pros
    •Usually taken only once daily with largest meal
    •Can lower A1C levels by 1.5%
    •Taken by mouth, so good option for people who don't like injections
    •Can be taken with some other blood sugar medications, such as metformin
    Cons
    •Risk of low blood sugar (hypoglycemia), especially if you have kidney or liver problems
    •More likely to cause low blood sugar than other blood sugar medications, such as metformin
    •Can cause some weight gain
    •Not approved for Type 1 diabetes

  • Common Side Effects of Toujeo vs. Glyburide

    Common Side Effects for
    •Low blood sugar
    •Common cold symptoms
    •Infection involving the nose, throat, and lungs
    Common Side Effects for
    •Feeling bloated
    •Nausea
    •Heartburn

  • Warnings of Toujeo vs. Glyburide

    Common Side Effects for
    •Risk of infections with pen sharing
    •Low blood sugar (hypoglycemia)
    •Low blood potassium levels
    •Swelling and heart failure when used with certain diabetes medications
    •Allergic reactions
    Common Side Effects for
    •Low blood sugar (hypoglycemia)
    •Possible risk of heart problems
    •Breakdown of red blood cells

  • Prices with our coupons for Toujeo vs. Glyburide

    Learn more about Toujeo
    Learn more about Glyburide

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