Key takeaways
Toujeo (insulin glargine) and glyburide (Glynase) are both used to manage diabetes, but they have some key differences. Toujeo is a long-acting insulin injected once daily to help control blood sugar levels in both Type 1 and Type 2 diabetes. It's available only as a brand-name medication and comes in prefilled pens. Toujeo works by helping your body absorb sugar from the bloodstream and store it for energy. Glyburide, on the other hand, is an oral medication that's typically taken once or twice daily and is used specifically for Type 2 diabetes. It belongs to the sulfonylurea class and works by stimulating the pancreas to release more insulin. Glyburide is available in both generic and brand-name forms. While Toujeo can cause low blood sugar and weight gain, glyburide also carries a risk of low blood sugar and may cause heartburn and nausea. Additionally, glyburide is not suitable for people with Type 1 diabetes or those experiencing diabetic ketoacidosis.
