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Compare Toujeo vs. Novolog

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Toujeo (insulin glargine) and NovoLog (insulin aspart) are both insulins used to manage diabetes, but they have some key differences. Toujeo is a long-acting insulin that you inject once a day, and it helps control your blood sugar levels for up to 36 hours. In contrast, NovoLog is a fast-acting insulin that you take multiple times a day, usually right before meals. It starts working within 15 minutes to manage blood sugar spikes from eating. Toujeo is only available as a brand-name medication, while NovoLog has several brand options like NovoLog FlexPen and NovoPen Echo. Toujeo is typically used for maintaining a baseline insulin level, whereas NovoLog is used to control blood sugar levels around mealtimes. Both can cause low blood sugar and weight gain, but NovoLog may also lead to accidental injuries due to more frequent injections and potential issues with insulin pumps.

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