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Compare Toujeo vs. Glucotrol

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Toujeo (insulin glargine) and Glucotrol XL (glipizide) are both used to manage diabetes, but they have some key differences. Toujeo is a long-acting insulin used for both Type 1 and Type 2 diabetes, and it's injected once daily under the skin. It helps your body absorb sugar from the bloodstream and store it for energy. On the other hand, Glucotrol XL is a sulfonylurea taken orally, typically once or twice daily, and is only used for Type 2 diabetes. It works by telling your pancreas to release more insulin. Toujeo is available only as a brand-name medication, while Glucotrol XL is available as a lower-cost generic. Both medications can cause low blood sugar, but Glucotrol XL must be taken with meals to prevent this, whereas Toujeo maintains a baseline insulin level throughout the day. Additionally, Toujeo can cause weight gain and requires careful storage, while Glucotrol XL can cause dizziness and has a risk of heart problems.

  • Toujeo (insulin glargine)
    Glipizide
  • Toujeo (insulin glargine)
    Glipizide

  • Summary of Toujeo vs. Glucotrol

    Summary for Insulin
    Prescription only

    Toujeo SoloStar and Toujeo Max SoloStar are a pair of brand names for insulin glargine. This medication is a long-acting insulin that's used for diabetes in adults and children. It's a more concentrated version of insulin glargine containing 300 units/mL. It comes as prefilled pens that you use for once-daily injections under the skin. Side effects include common cold symptoms and low blood sugar.

    Summary for Sulfonylurea
    Prescription only

    Glipizide is a sulfonylurea medication used to treat Type 2 diabetes in adults. It lowers blood sugar levels by telling your pancreas to release more insulin. Glipizide is taken by mouth, typically once or twice daily. Some side effects of this medication include dizziness and diarrhea. Taking glipizide can also put you at risk for dangerously low blood sugar, so it's important to take this medication with meals.

  • Indications of Toujeo vs. Glucotrol

    Indications for
    •Type 1 diabetes
    •Type 2 diabetes
    Indications for
    •Type 2 diabetes

  • Pros and Cons of Toujeo vs. Glucotrol

    Pros and Const for Insulin
    Pros
    •Long-lasting insulin that provides consistent, all-day blood sugar control
    •Given once a day
    •Available as a prefilled pen
    •Good choice for people who need high doses of long-acting insulin
    •Can use in children as young as 6 years old
    Cons
    •Must inject the medication under the skin
    •Might be difficult for some people to administer correctly
    •Can cause weight gain and low blood sugar (hypoglycemia)
    •Can't be mixed with other insulins
    Pros and Const for Sulfonylurea
    Pros
    •Taken by mouth
    •Extended-release tablets taken once daily
    •Available as a lower-cost generic medication
    Cons
    •Raises your risk for low blood sugar levels (hypoglycemia)
    •Need to take with meals or 30 minutes before a meal
    •Can cause some weight gain as a side effect

  • Common Side Effects of Toujeo vs. Glucotrol

    Common Side Effects for
    •Low blood sugar
    •Common cold symptoms
    •Infection involving the nose, throat, and lungs
    Common Side Effects for
    •Dizziness (7%)
    •Diarrhea (5%)
    •Nervousness (4%)
    •Tremor (4%)
    •Passing gas (3%)
    •Low blood sugar levels (3%)

    Note: Side effects were reported by people who took glipizide ER (Glucotrol XL) in clinical studies.

  • Warnings of Toujeo vs. Glucotrol

    Common Side Effects for
    •Risk of infections with pen sharing
    •Low blood sugar (hypoglycemia)
    •Low blood potassium levels
    •Swelling and heart failure when used with certain diabetes medications
    •Allergic reactions
    Common Side Effects for
    •Low blood sugar levels
    •Risk of low red blood cell count (hemolytic anemia)
    •Possible risk of serious heart problems
    •Risk of harm in people with certain stomach problems (extended-release tablets)

  • Prices with our coupons for Toujeo vs. Glucotrol

    Learn more about Toujeo
    Learn more about Glipizide

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