Key takeaways
Novolin N (insulin NPH) and glyburide (Glynase) are both used to manage diabetes, but they work in different ways and have different uses. Novolin N is an intermediate-acting insulin that you inject under the skin to help control blood sugar levels throughout the day. It can be used for both Type 1 and Type 2 diabetes and is available by prescription or over the counter. On the other hand, glyburide is a prescription oral medication that is only used for Type 2 diabetes and is taken once or twice daily with meals. It works by stimulating your pancreas to release more insulin. While both medications can cause low blood sugar, Novolin N has a higher risk compared to glyburide. The risk of low blood sugar is higher in people with liver or kidney problems. Novolin N is only available as a brand medication, while glyburide is available as a lower-cost generic.
