Skip to main content

Biguanides

Biguanides are used to treat diabetes type 2. They lower blood sugar levels by decreasing the amount of glucose absorbed through the intestines and made by the liver. They also work by making the body more sensitive to insulin.

Why are biguanides prescribed?

  1. Diabetes Type 2 (100%)

Key takeaways

Biguanides are used to treat type 2 diabetes. They work by decreasing the amount of sugar your liver makes and improving your body's response to insulin. These medications are available in as oral forms, either as immediate-release or extended-release tablets. Examples include metformin (Glucophage) and metformin extended-release (Glucophage XR, Fortamet). You can choose the form that best fits your needs.

Prices for popular Biguanides medications
Viewing 6 of 6 medications
Metformin (Glucophage) is an inexpensive drug used to treat high blood sugar levels caused by type 2 diabetes. It is more popular than comparable drugs. It is available in both brand and generic versions. Generic metformin is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Riomet (metformin) is used to treat type 2 diabetes. Riomet is less popular than other biguanides. Riomet is available in generic and brand versions.

Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Riomet is covered by some Medicare and insurance plans.
Metformin ER (Glucophage XR) is an inexpensive drug used to treat type II diabetes. It helps control blood sugar in combination with diet and exercise. This drug is slightly more popular than comparable drugs. It is available in brand and generic versions. Generic metformin ER is covered by most Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
Metformin ER is a biguanide used to treat type II diabetes. It helps control blood sugar in combination with diet and exercise. Metformin is widely considered the first-line treatment for adult onset diabetes because it rarely causes hypoglycemia and can help with weight loss. Brands include Fortamet and Glucophage XR. The immediate release version is available as generic metformin and Glucophage. Extended-release metformin combination pills include Janumet XR (Januvia and metformin) and Actoplus Met XR (pioglitazone and metformin).
Metformin ER (Fortamet) is an expensive drug used to treat type II diabetes. It helps control blood sugar in combination with diet and exercise. This drug is slightly less popular than comparable drugs. It is available in brand and generic versions. It is covered by some Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
oral-solution icon

Riomet ER

as low as$768
METFORMIN treats type 2 diabetes. It controls blood sugar (glucose) and helps your body use insulin effectively. This medication is often combined with changes to diet and exercise.
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

Subscribe and save

Get prescription saving tips and more from GoodRx Health. Enter your email to sign up

By signing up, I agree to GoodRx’s Terms of Use and Privacy Policy, and to receive marketing messages from GoodRx.

Latest Articles

Browse medications

View All
Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.