HomeHealth Topic

Heart Disease: Your GoodRx Guide

Sophie Vergnaud, MDMandy Armitage, MD
Written by Sophie Vergnaud, MD | Reviewed by Mandy Armitage, MD
Published on September 13, 2021


The term “heart disease” is usually taken to mean coronary heart disease or coronary artery disease. But it can also refer to the wide range of conditions that affect the heart, from problems with how the heart beats (arrhythmias) to diseases of the heart muscle or valves, and even the blood vessels.

You might feel like you hear about heart disease a lot, and that’s for good reason: Heart disease is the leading cause of death in the U.S. for most racial groups. And in the following groups of women, heart disease is the second most common cause of death, after cancer:

  • American Indian

  • Alaska Native

  • Hispanic

  • Asian American and Pacific Islander

To put it in perspective, 1 in every 4 U.S. deaths is caused by heart disease (that’s 655,000 deaths in total). In 2017 alone, 366,000 deaths were caused by coronary artery disease.


High Lp(a) Is an Inherited Heart Risk

1 in 5 Americans has high Lp(a), which can increase the risk of heart attack and stroke by 2-4x

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The most common type of heart disease is coronary heart disease, or coronary artery disease. It is responsible for conditions like:

Coronary heart disease is caused by something called atherosclerosis. When you have atherosclerosis, a fatty, gritty plaque builds up within blood vessels called arteries. Over time, this makes arteries narrower and stiffer, often causing high blood pressure. The rough surface of the fatty plaque can also break off and cause blood vessel blockages downstream.

Atherosclerosis can happen to arteries anywhere in the body. When it happens to arteries in the neck and brain, it can cause strokes. Atherosclerosis in the arms and legs causes peripheral artery disease. And when the arteries that supply the heart (coronary arteries) narrow and stiffen, it causes angina and heart attacks.

Sometimes, people are born with heart conditions (called congenital heart disease), and sometimes heart disease can’t be avoided (such as with infections that cause heart disease).

Risk factors

More commonly, there are medical conditions or life triggers that increase risk for heart disease. Examples include:

But that’s not all — other factors play a part too, including your:

  • Family history

  • Stress

  • Race

  • Genetics


Symptoms of heart disease are different for each person and for every diagnosis. But common heart disease symptoms include:

  • Chest tightness

  • Chest pain

  • Difficulty breathing

  • Palpitations

  • Fatigue

  • Leg swelling

  • Passing out


Many types of heart disease — and their risk factors — are silent early on. That’s why it’s so important to learn about heart disease, your own personal risk, and how to balance that risk with positive lifestyle changes and, when needed, medication.

Read on to explore trustworthy, expert-reviewed information on how to keep your heart healthy — whether you have a diagnosis of heart disease or not.


American Heart Association. (2020). Atherosclerosis.

Benjamin, E. J., et al. (2019). Heart disease and stroke statistics—2019 update: A report from the American Heart Association. Circulation.

View All References (3)

British Heart Foundation. (n.d.). 11 signs you might have heart disease.

Centers for Disease Control and Prevention. (2019). Know your risk for heart disease.

Centers for Disease Control and Prevention. (2022). Heart disease facts.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

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