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Farxiga vs. Glipizide

Farxiga, the brand name for dapagliflozin, is used together with a nutritious diet and exercise plan to lower blood sugar levels in people 10 years and older with Type 2 diabetes. It can also help lower the risk of serious complications, hospitalization, and death in certain adults with heart failure or chronic kidney disease (CKD). Farxiga (dapagliflozin) belongs to the drug class called sodium-glucose cotransporter 2 (SGLT2) inhibitors. It's taken by mouth once a day. Some side effects include yeast infections, urinating more often, and weight loss.

• Type 2 diabetes (in addition to diet and exercise) in people age 10 and over
• Lowering the risk of hospitalization for heart failure in adults with Type 2 diabetes and heart disease
• Lowering the risk of hospitalization and death due to heart problems in people with heart failure
• Lowering the risk of worsening kidney problems, hospitalization for heart failure, and death due to heart problems in adults with chronic kidney disease (CKD)

• Vaginal yeast infection in females (7-8%)
• Nose and throat infection (6-7%)
• Urinary tract infection (UTI, 4-6%)

• Ketoacidosis
• Low fluids in the body (leading to low blood pressure or dehydration)
• Genital and urinary tract infections
• Low blood sugar (hypoglycemia) when used with other diabetes medications

Glipizide is a sulfonylurea medication used to treat Type 2 diabetes in adults. It lowers blood sugar levels by telling your pancreas to release more insulin. Glipizide is taken by mouth, typically once or twice daily. Some side effects of this medication include dizziness and diarrhea. Taking glipizide can also put you at risk for dangerously low blood sugar, so it's important to take this medication with meals.

• Type 2 diabetes

• Dizziness (7%)
• Diarrhea (5%)
• Nervousness (4%)
• Tremor (4%)
• Passing gas (3%)
• Low blood sugar levels (3%)

Note: Side effects were reported by people who took glipizide ER (Glucotrol XL) in clinical studies.

• Low blood sugar levels
• Risk of low red blood cell count (hemolytic anemia)
• Possible risk of serious heart problems
• Risk of harm in people with certain stomach problems (extended-release tablets)