Key takeaways
Metformin (Glucophage) and Afrezza (inhaled insulin) are both medications used to manage diabetes, but they work in different ways. Metformin is taken orally and is primarily used for Type 2 diabetes. It helps lower the amount of sugar your body makes or absorbs and improves your body's use of insulin. Afrezza, on the other hand, is a fast-acting insulin inhaled through the mouth and is used for both Type 1 and Type 2 diabetes. It helps your body absorb and store sugar from your bloodstream after meals. Metformin rarely causes weight gain or low blood sugar, but it can cause stomach issues like diarrhea and nausea. Afrezza is a good option for those who dislike injections, but it can cause low blood sugar, cough, and throat irritation, and isn’t suitable for people with breathing problems like asthma or COPD. Additionally, Afrezza is not recommended for smokers or those who have recently quit smoking.
