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Clomiphene vs. Metformin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Clomid

(clomiphene)

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Metformin

 

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Summary for Clomiphene

Prescription only

Clomid (clomiphene) is a selective estrogen receptor modulator (SERM) used to treat infertility in people wanting to become pregnant. It works by causing ovulation, or egg release. You'll take a dose by mouth every day for 5 days, typically during your menstrual period. Some of the more common side effects include hot flashes, bloating, and stomach pain.

Indications for Clomiphene

Pros and Cons for Clomiphene

Pros

Cons

  • Typically only recommended for up to 3 cycles, not a long-term treatment
  • Can cause vision problems in some rare cases
  • Not safe if you have liver problems or certain thyroid problems

Common Side Effects for Clomiphene

  • Swollen ovaries (14%)
  • Hot flashes (10%)
  • Stomach pain, discomfort, or bloating (6%)

Warnings for Clomiphene

  • Vision changes
  • Ovarian hyperstimulation syndrome (OHSS)
  • Possible risk of harm to unborn baby

Summary for Metformin

Prescription only

Immediate-release metformin is an oral diabetes medication. It's approved for people 10 years of age and older with Type 2 diabetes. The medication belongs to the drug class called biguanides. It works best to lower blood sugar levels with a diabetes-friendly diet and exercise plan. Immediate-release metformin comes as a tablet and an oral solution. You take this medication by mouth usually two to three times a day. It's recommended to take each dosage with food to help lessen side effects like diarrhea and nausea.

Indications for Metformin

Pros and Cons for Metformin

Pros

Cons

  • Typically need to take a couple times per day
  • Can cause stomach upset, including diarrhea, nausea, gas, and stomach cramping
  • Not a good choice for people with severe kidney problems
  • Not recommended for people with liver problems

Common Side Effects for Metformin

  • Diarrhea (53%)
  • Nausea or vomiting (26%)
  • Gas (12%)
  • Weakness (9%)

Warnings for Metformin

  • Lactic acidosis
  • Low vitamin B12 levels
  • Low blood sugar (hypoglycemia) when taken with certain other diabetes medications

Prices with our coupons for Clomiphene vs. Metformin

Price Card Drug Icon
Clomid30 tablets / 50mg
$111.49-
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Price Card Drug Icon
Metformin60 tablets / 500mg
$9.00$9.00
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