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Clomiphene vs. HCG

Clomid (clomiphene) is a selective estrogen receptor modulator (SERM) used to treat infertility in people wanting to become pregnant. It works by causing ovulation, or egg release. You'll take a dose by mouth every day for 5 days, typically during your menstrual period. Some of the more common side effects include hot flashes, bloating, and stomach pain.

• Female infertility

• Swollen ovaries (14%)
• Hot flashes (10%)
• Stomach pain, discomfort, or bloating (6%)

• Vision changes
• Ovarian hyperstimulation syndrome (OHSS)
• Possible risk of harm to unborn baby

Human chorionic gonadotropin (hCG) is a hormone that's naturally made in the body during pregnancy. It's also very similar to luteinizing hormone (LH), a hormone involved in reproduction in males and females. As a medication, HCG (Pregnyl, Novarel) is used for fertility treatments in females. It's also used in certain cases to raise testosterone levels in males and to help the testes descend in males who haven't yet reached puberty (cryptorchidism). HCG is injected into the muscles (or as directed by your provider), typically a few times a week. Some common side effects of HCG can include headache, irritability, and feeling restless.

• Female infertility
• Low testosterone levels in males (hypogonadism) caused by pituitary gland condition
• Prepubertal cryptorchidism (a condition where the testes haven't descended)

• Headache
• Irritability
• Restlessness
• Depression
• Fatigue or tiredness
• Edema (swelling)
• Early puberty
• Growth of breasts in males
• Pain at injection site

• Severe allergic reactions, including anaphylaxis (closing of the throat)
• Ovarian hyperstimulation syndrome (OHSS)
• Blood clots
• Getting pregnant with more than one baby
• Early puberty
• Risk of cancer with use for male infertility caused by hypogonadism
• Water retention