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Compare Brenzavvy vs. Jardiance

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Brenzavvy (bexagliflozin) and Jardiance (empagliflozin) are both medications in the sodium-glucose cotransporter 2 (SGLT2) inhibitor medication class. They are used to help manage Type 2 diabetes by lowering blood sugar levels. Brenzavvy and Jardiance work by preventing sugar from being reabsorbed in the kidneys, which helps remove excess sugar through the urine. However, Jardiance (empagliflozin) has additional FDA-approved uses, including reducing the risk of heart-related complications in adults with heart failure or chronic kidney disease, while Brenzavvy (bexagliflozin) is only approved for Type 2 diabetes. Brenzavvy is typically taken as a 20 mg tablet once daily, whereas Jardiance starts at 10 mg and can be increased to 25 mg in some cases. Neither medication is available in a generic form. Common side effects for both include urinary tract infections, yeast infections, and increased urination. Both medications can increase the risk of low blood sugar and low blood pressure, especially combined with other medications that have those effects.

  • Brenzavvy (bexagliflozin)
    Jardiance (empagliflozin)
  • Brenzavvy (bexagliflozin)
    Jardiance (empagliflozin)

  • Summary of Brenzavvy vs. Jardiance

    Summary for SGLT2 inhibitor
    Prescription only

    Brenzavvy (bexagliflozin) is a newly-approved medication that's used along with a healthy diet and exercise to lower blood sugar levels in people with Type 2 diabetes. This medication is a tablet that's taken by mouth every day in the morning. The most common side effects of Brenzavvy (bexagliflozin) are more frequent urinary tract infections (UTIs) and urinating more than usual since it works to remove blood sugar from your body through the urine.

    Summary for SGLT2 inhibitor
    Prescription only

    Jardiance (empagliflozin) is a brand-name medication that's used along with a nutritious diet and routine exercise to improve blood sugar levels in people 10 years and older with Type 2 diabetes. It can also lower the chance of serious complications, hospitalization, and death in certain adults with heart failure or chronic kidney disease (CKD). Jardiance (empagliflozin) belongs to the drug class called sodium-glucose cotransporter 2 (SGLT2) inhibitors. It's a tablet that's taken by mouth once a day. Side effects can include urinary tract infections (UTIs), yeast infections, and weight loss.

  • Indications of Brenzavvy vs. Jardiance

    Indications for
    •Type 2 diabetes
    Indications for
    •Type 2 diabetes (in addition to diet and exercise) in people age 10 years and older
    •Lowering the risk of death due to heart problems in adults with Type 2 diabetes and heart disease
    •Lowering the risk of hospitalization and death due to heart problems in adults with heart failure
    •Lowering the risk of worsening kidney problems, hospitalization, and death due to heart problems in adults with chronic kidney disease (CKD)

  • Pros and Cons of Brenzavvy vs. Jardiance

    Pros and Const for SGLT2 inhibitor
    Pros
    •Taken only once a day
    •Can use alone or together with other diabetes medications
    •Not likely to cause weight gain
    Cons
    •Might cause more urination or urinary infections
    •Not recommended in second and third trimesters of pregnancy
    •Not a good option for people with severe kidney problems or on dialysis
    Pros and Const for SGLT2 inhibitor
    Pros
    •Taken by mouth once a day
    •Unlikely to cause weight gain
    •Can take with other diabetes medications
    Cons
    •Raises risk of urinary tract infections (UTIs) and genital yeast infections
    •Might make you urinate more
    •Not recommended during the second and third trimesters of pregnancy

  • Common Side Effects of Brenzavvy vs. Jardiance

    Common Side Effects for
    •More urination (7%)
    •Urinary tract infection (6%)
    •Vaginal yeast infection in women (6%)
    Common Side Effects for
    •Urinary tract infection (UTI; 8-9%)
    •Vaginal yeast infection in females (5-6%)
    •Upper respiratory tract infection (3-4%)
    •High cholesterol or fat levels (3-4%)
    •Urinating more than usual (3%)

  • Warnings of Brenzavvy vs. Jardiance

    Common Side Effects for
    •Ketoacidosis
    •Lower limb amputation
    •Low fluids in the body (leading to low blood pressure or dehydration)
    •Genital and urinary tract infections
    •Low blood sugar (hypoglycemia) when used with certain other diabetes medications
    Common Side Effects for
    •Ketoacidosis
    •Low fluids in the body (leading to low blood pressure or dehydration)
    •Genital and urinary tract infections
    •Low blood sugar (hypoglycemia) when used with certain other diabetes medications
    •Leg and foot amputations
    •Allergic reactions

  • Prices with our coupons for Brenzavvy vs. Jardiance

    Learn more about Brenzavvy
    Learn more about Jardiance

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