Key takeaways
Glucovance (glyburide/metformin) and Jardiance (empagliflozin) are both medications used to manage Type 2 diabetes, but they some differences between them. Glucovance combines glyburide, which stimulates insulin release, and metformin, which works to reduces sugar production and absorption. Jardiance helps your kidneys remove excess sugar through your urine. Unlike Jardiance, Glucovance is available as a lower-cost generic. It's best to take Glucovance with meals to avoid low blood sugar and stomach upset. Jardiance can be taken once daily, with or without food. Jardiance also offers additional benefits for adults with heart failure and chronic kidney disease. And taking Jardiance can increase your risk of urinary tract and yeast infections. Both medications can cause low blood sugar, especially when combined with other diabetes treatments, but this risk is higher in people taking Glucovance.
