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Compare Ilumya vs. Skyrizi

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Ilumya (tildrakizumab)
    Skyrizi (risankizumab)
  • Ilumya (tildrakizumab)
    Skyrizi (risankizumab)

  • Summary of Ilumya vs. Skyrizi

    Summary for Interleukin-23 antagonist
    Prescription only

    Ilumya (tildrakizumab or tildrakizumab-asmn) is used to treat plaque psoriasis in adults. It's a type of monoclonal antibody called an interleukin-23 antagonist. It works by lowering inflammation in the skin. This medication is given as an injection under the skin every 3 months by a healthcare professional. Some people might have upper respiratory tract infections as a side effect. Ilumya (tildrakizumab) is only available as a brand-name medication.

    Summary for Interleukin antagonist
    Prescription only

    Skyrizi (risankizumab or risankizumab-rzaa) is an injection used to treat different inflammatory conditions in adults. This includes plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis. It belongs to the drug class called interleukin antagonists. It works to lower inflammation and relieve symptoms. After the first few doses, you usually get the Skyrizi (risankizumab) injection every 2 or 3 months. This medication can raise your risk of infection as a side effect.

  • Indications of Ilumya vs. Skyrizi

    Indications for
    •Moderate-to-severe plaque psoriasis
    Indications for
    •Moderate-to-severe plaque psoriasis in adults
    •Psoriatic arthritis in adults
    •Moderate-to-severe Crohn's disease in adults
    •Moderate-to-severe ulcerative colitis in adults

  • Pros and Cons of Ilumya vs. Skyrizi

    Pros and Const for Interleukin-23 antagonist
    Pros
    •Only given every 3 months, after the first two doses
    •Few side effects
    Cons
    •Needs to be injected by a healthcare professional, not on your own at home
    •Not approved for other skin problems or autoimmune conditions
    Pros and Const for Interleukin antagonist
    Pros
    •Given every 2 or 3 months after a couple of starter doses (depends on your condition)
    •Can give injections under the skin at home after you get trained
    Cons
    •Must be given as an injection
    •Not approved for children

  • Common Side Effects of Ilumya vs. Skyrizi

    Common Side Effects for
    •Upper respiratory infections (14%)
    Common Side Effects for
    •Upper respiratory infections (13%)
    •Headache (4%)
    •Tiredness (3%)

  • Warnings of Ilumya vs. Skyrizi

    Common Side Effects for
    •Serious allergic reactions
    •Higher risk of infections
    •Avoid live vaccines
    Common Side Effects for
    •Allergic reaction
    •Risk of infection
    •Rare case of liver injury
    •Caution when getting vaccines

  • Prices with our coupons for Ilumya vs. Skyrizi

    Learn more about Ilumya
    Learn more about Skyrizi

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