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Bimzelx vs. Skyrizi

Bimzelx (bimekizumab or bimekizumab-bkzx) is an injection that's used to treat several inflammatory conditions in adults. They include plaque psoriasis, psoriatic arthritis, and hidradenitis suppurativa, to name a few. It's a type of monoclonal antibody called an interleukin antagonist. It works to reduce inflammation in the body. Bimzelx (bimekizumab) comes in prefilled autoinjectors or prefilled syringes. You inject the medication under the skin either every month or every other month. It can cause side effects like upper respiratory infections.

• Moderate-to-severe plaque psoriasis
• Psoriatic arthritis
• Non-radiographic axial spondyloarthritis
• Ankylosing spondylitis
• Moderate-to-severe hidradenitis suppurativa

• Upper respiratory tract infection (runny nose, sore throat; 15%)
• Oral thrush (9%)
• Headache (3%)
• Injection site reactions (redness, pain, swelling, bruising; 3%)
• Fungal skin infections (3%)

• Suicidal thoughts or behavior
• Risk of infections
• Liver problems
• Inflammatory bowel disease
• Interaction with vaccines

Skyrizi (risankizumab or risankizumab-rzaa) is an injectable medication for many inflammatory conditions. It treats plaque psoriasis in adults and children ages 6 years and up. It can also treat psoriatic arthritis, Crohn's disease, and ulcerative colitis in adults. This medication works as an interleukin antagonist to help lower inflammation. After a few starter doses, it's given every 2 or 3 months, depending on the condition being treated. Side effects include a higher risk of infection.

• Moderate-to-severe plaque psoriasis in adults and children ages 6 years and older
• Psoriatic arthritis in adults
• Moderate-to-severe Crohn's disease in adults
• Moderate-to-severe ulcerative colitis in adults

• Upper respiratory infections (13%)
• Headache (4%)
• Tiredness (3%)

• Allergic reaction
• Risk of infection
• Rare case of liver injury
• Caution when getting vaccines