Bimzelx vs. Skyrizi for Plaque Psoriasis: Important Differences and Potential Risks.

Bimzelx

(bimekizumab)

Skyrizi

(risankizumab)

Summary for Bimzelx

Prescription only

Bimzelx (bimekizumab or bimekizumab-bkzx) is an injection that's used to treat several inflammatory conditions in adults. They include plaque psoriasis, psoriatic arthritis, and hidradenitis suppurativa, to name a few. It's a type of monoclonal antibody called an interleukin antagonist. It works to reduce inflammation in the body. Bimzelx (bimekizumab) comes in prefilled autoinjectors or prefilled syringes. You inject the medication under the skin either every month or every other month. It can cause side effects like upper respiratory infections.

Indications for Bimzelx

Moderate-to-severe plaque psoriasis
Psoriatic arthritis
Non-radiographic axial spondyloarthritis
Ankylosing spondylitis
Moderate-to-severe hidradenitis suppurativa

Pros and Cons for Bimzelx

Pros

Dosing schedule is either every month or every other month, so it's convenient for most people
An option for plaque psoriasis if topical medications have stopped working
Available as prefilled autoinjectors and prefilled syringes

Cons

Can cause injection reactions, such as pain, bruising, and swelling
Might raise the risk of infections
Unknown if safe during pregnancy or while breastfeeding

Common Side Effects for Bimzelx

Upper respiratory tract infection (runny nose, sore throat; 15%)
Oral thrush (9%)
Headache (3%)
Injection site reactions (redness, pain, swelling, bruising; 3%)
Fungal skin infections (3%)

Warnings for Bimzelx

Suicidal thoughts or behavior
Risk of infections
Liver problems
Inflammatory bowel disease
Interaction with vaccines

Summary for Skyrizi

Prescription only

Skyrizi (risankizumab or risankizumab-rzaa) is an injectable medication for many inflammatory conditions. It treats plaque psoriasis in adults and children ages 6 years and up. It can also treat psoriatic arthritis, Crohn's disease, and ulcerative colitis in adults. This medication works as an interleukin antagonist to help lower inflammation. After a few starter doses, it's given every 2 or 3 months, depending on the condition being treated. Side effects include a higher risk of infection.

Indications for Skyrizi

Moderate-to-severe plaque psoriasis in adults and children ages 6 years and older
Psoriatic arthritis in adults
Moderate-to-severe Crohn's disease in adults
Moderate-to-severe ulcerative colitis in adults

Pros and Cons for Skyrizi

Pros

Given every 2 or 3 months after the starter doses (depends on your condition)
Can give maintenance doses at home as injections under the skin after proper training
Approved for children as young as 6 years old with plaque psoriasis

Cons

Must be given as an injection
Can raise the risk of infection
Might take several weeks to months to work fully

Common Side Effects for Skyrizi

Upper respiratory infections (13%)
Headache (4%)
Tiredness (3%)

Warnings for Skyrizi

Allergic reaction
Risk of infection
Rare case of liver injury
Caution when getting vaccines

Prices with our coupons for Bimzelx vs. Skyrizi

Bimzelx1 carton / 1 autoinjector of 320mg/2ml

$16,039.69-

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Skyrizi1 package / 1 pen of 150mg/ml

$20,217.99-

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Bimzelx vs. Skyrizi

Bimzelx

Skyrizi

Summary for Bimzelx

Indications for Bimzelx

Pros and Cons for Bimzelx

Pros

Cons

Common Side Effects for Bimzelx

Warnings for Bimzelx

Summary for Skyrizi

Indications for Skyrizi

Pros and Cons for Skyrizi

Pros

Cons

Common Side Effects for Skyrizi

Warnings for Skyrizi

Prices with our coupons for Bimzelx vs. Skyrizi

Compare other Plaque Psoriasis drugs

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Bimzelx

Skyrizi

Summary for Bimzelx

Indications for Bimzelx

Pros and Cons for Bimzelx

Pros

Cons

Common Side Effects for Bimzelx

Warnings for Bimzelx

Summary for Skyrizi

Indications for Skyrizi

Pros and Cons for Skyrizi

Pros

Cons

Common Side Effects for Skyrizi

Warnings for Skyrizi