Popular Insomnia Drugs

Popularity Drug Name Drug Class Price Price Trend
GABA Agonists 7
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Zolpidem (Ambien) is an inexpensive drug used to treat insomnia. It is more popular than comparable drugs. It is available in generic and brand versions. Generic zolpidem is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
GABA Agonists 7
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Zolpidem (Ambien) is an inexpensive drug used to treat insomnia. It is more popular than comparable drugs. It is available in generic and brand versions. Generic zolpidem is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Benzodiazepines 9
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TEMAZEPAM is a benzodiazepine. It is used to help you to fall asleep and sleep through the night.
GABA Agonists 22
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ESZOPICLONE is used to treat insomnia. This medicine helps you to fall asleep and sleep through the night.
Antihistamines N/A N/A See Prices
Unisom (diphenhydramine or doxylamine) is an antihistamine used as an over-the-counter sleep aid. Antihistamines often cause drowsiness and sedation and can be used to help with difficult falling asleep. Unisom capsules and chewable tablets have diphenhydramine as an active ingredient, and the tablets have doxylamine; both are available as generic antihistamine sleep aids.
Antihistamines N/A N/A See Prices
ZzzQuil (diphenhydramine) is an antihistamine used as an over-the-counter sleep aid. Antihistamines often cause drowsiness and sedation and can be used to help with difficult falling asleep. ZzzQuil includes only the sleep-aid active ingredient from NyQuil, without the other ingredients to treat cough and cold symptoms. Diphenhydramine is also available as a generic, and under other brand names including Benadryl and Unisom.
GABA Agonists 49
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ZOLPIDEM is used to treat insomnia. This medicine helps you to fall asleep and sleep through the night.
Benzodiazepines 33
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TRIAZOLAM is a benzodiazepine. It is used to treat insomnia. This medicine helps you to sleep. It is only for short-term use, and should generally be used for no more than 2 to 3 weeks.
GABA Agonists 15
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ZALEPLON is used to treat insomnia. This medicine helps you to fall asleep.
Orexin Receptor Antagonists 292
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SUVOREXANT (su-vor-EX-ant) is used to treat insomnia. This medicine helps you to fall asleep and sleep through the night.
Melatonin Receptor Agonists 344
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RAMELTEON is used to treat insomnia. This medicine helps you to fall asleep.
Benzodiazepines 18
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FLURAZEPAM is a benzodiazepine. It is used to treat insomnia. This medicine helps you to fall asleep and sleep through the night.
Tricyclic Antidepressants 376
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DOXEPIN is used to treat insomnia. This medicine helps you sleep through the night.
Benzodiazepines 19
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ESTAZOLAM is a benzodiazepine. It is used to treat insomnia. This medicine helps you to fall asleep and sleep through the night.
Multivitamin and Mineral Supplements N/A N/A See Prices
MELATONIN is a dietary supplement. It is mostly promoted to help maintain normal sleep patterns. The FDA has not approved this supplement for any medical use.
GABA Agonists 377
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ZOLPIDEM is used to treat insomnia. Edluar is for use when you have trouble falling asleep when you first go to bed. Intermezzo is for use when you have trouble returning to sleep after waking in the middle of the night.
Barbiturates 126
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BUTABARBITAL is a barbiturate. It is used to help you relax for sleep.
GABA Agonists 46
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ZOLPIDEM is used to treat insomnia. This medicine helps you to fall asleep and sleep through the night.
Melatonin Receptor Agonists 12,382
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TASIMELTEON is used to treat sleep-wake cycle disruptions in people who are blind.
Benzodiazepines N/A N/A See Prices
Quazepam is a benzodiazepine. It is used to treat insomnia. This medicine helps you to fall asleep and sleep through the night.
Benzodiazepines 653
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Quazepam is a benzodiazepine. It is used to treat insomnia. This medicine helps you to fall asleep and sleep through the night.
Antihistamine / Non-narcotic Antitussive Combinations N/A N/A See Prices
Barbiturates 975
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NSAID Cough and Cold Combinations N/A N/A See Prices
DIPHENHYDRAMINE; IBUPROFEN is a combination of a sleep-aid and a non-steroidal anti-inflammatory drug (NSAID). It is used to treat occasional sleeplessness with minor aches and pains.
NSAID Cough and Cold Combinations N/A N/A See Prices
DIPHENHYDRAMINE; IBUPROFEN is a combination of a sleep-aid and a non-steroidal anti-inflammatory drug (NSAID). It is used to treat occasional sleeplessness with minor aches and pains.
Acetaminophen Combinations N/A N/A See Prices
Acetaminophen Combinations N/A N/A See Prices
ACETAMINOPHEN; DEXTROMETHORPHAN; DOXYLAMINE is a combination of a pain reliever, a cough suppressant, and an antihistamine. It is used to treat the aches and pains, cough, fever, headache, runny nose, and sneezing of a cold. This medicine will not treat an infection.
Acetaminophen Combinations N/A N/A See Prices
Acetaminophen Combinations N/A N/A See Prices
Acetaminophen Combinations N/A N/A See Prices
ACETAMINOPHEN; DIPHENHYDRAMINE is a pain reliever antihistamine combination. It is used to treat allergy symptoms like sore throat, runny nose, sneezing, and itching of the eyes, nose, and throat. Or, this medicine is used to treat pain and help you fall to sleep.

Note: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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