Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Zaleplon (Sonata) and diazepam (Valium) are both prescription medications that can help with sleep, but they belong to different drug classes and have different uses. Zaleplon is a non-benzodiazepine sedative-hypnotic, often called a "z-drug," and is specifically used for treating insomnia by helping you fall asleep. Diazepam, on the other hand, is a benzodiazepine used for a variety of conditions, including anxiety, alcohol withdrawal, muscle spasms, and as an add-on for seizures. Diazepam may sometimes be used off-label for insomnia. Zaleplon is taken by mouth right before bedtime and works quickly. The usual diazepam dosage depends on what it is being used for. Both are available in a lower-cost generic version. Common side effects of zaleplon include headache and dizziness, while diazepam can cause sleepiness, dizziness, and muscle weakness. Both medications carry a risk of misuse and dependence and are controlled substances.
Zaleplon
Diazepam (Valium)
Zaleplon
Diazepam (Valium)
Summary of Sonata vs. Valium
Summary for Sedative-hypnotic
Prescription only
Zaleplon, once sold under the brand name Sonata, is a prescription sleep medication for adults. It helps with insomnia (trouble falling asleep). It's a type of sedative-hypnotic called a non-benzodiazepine, or "z-drug." You take it by mouth right before bed or when you're already in bed and can't fall asleep. Zaleplon is a controlled substance because it has a risk of misuse and dependence. Side effects can include headache and dizziness.