Key takeaways
Zaleplon (Sonata) and diazepam (Valium) are both prescription medications that can help with sleep, but they belong to different drug classes and have different uses. Zaleplon is a non-benzodiazepine sedative-hypnotic, often called a "z-drug," and is specifically used for treating insomnia by helping you fall asleep. Diazepam, on the other hand, is a benzodiazepine used for a variety of conditions, including anxiety, alcohol withdrawal, muscle spasms, and as an add-on for seizures. Diazepam may sometimes be used off-label for insomnia. Zaleplon is taken by mouth right before bedtime and works quickly. The usual diazepam dosage depends on what it is being used for. Both are available in a lower-cost generic version. Common side effects of zaleplon include headache and dizziness, while diazepam can cause sleepiness, dizziness, and muscle weakness. Both medications carry a risk of misuse and dependence and are controlled substances.
