Key takeaways
Zaleplon (Sonata) and lorazepam (Ativan) are both prescription medications to help with sleep, but they belong to different drug classes. Zaleplon is a non-benzodiazepine sedative-hypnotic, often called a "z-drug," and is specifically used for treating insomnia by helping you fall asleep. Lorazepam, on the other hand, is a benzodiazepine primarily used for anxiety disorders, but can also help with sleep due to its calming effects. Zaleplon is taken orally right before bed and works quickly, within about 30 minutes, but it doesn't help you stay asleep throughout the night. For sleep, lorazepam is usually 1 tablet by mouth at night, with effects felt within 30 minutes to 2 hours. Both medications are controlled substances because they can lead to misuse and dependence. Common side effects of both medications include sleepiness and dizziness. It's important to avoid alcohol with both medications, as it can increase the risk of serious side effects.
