Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Lunesta (eszopiclone) and flurazepam are both medications used to treat insomnia, but they belong to different drug classes. Lunesta is a sedative-hypnotic, while flurazepam is a benzodiazepine. Both medications are available in generic forms and are controlled substances due to their potential for misuse and dependence. Lunesta is typically taken right before bedtime and can cause side effects like a bad taste in the mouth and headache. Flurazepam, on the other hand, is usually taken at bedtime and can cause side effects such as headache, upset stomach, and dizziness. Lunesta works by interacting with GABA proteins in the brain to promote sleep, although its exact mechanism is not fully understood. Flurazepam calms the nervous system by affecting brain chemicals. Both medications can cause abnormal sleep behaviors like sleepwalking and sleep-driving, but flurazepam has a higher risk of addiction and misuse. Additionally, flurazepam is not recommended for use during pregnancy, while Lunesta should be used with caution in older adults and those with severe liver problems.
Lunesta (eszopiclone)
Flurazepam
Lunesta (eszopiclone)
Flurazepam
Summary of Lunesta vs. Dalmane
Summary for Sedative-hypnotic
Prescription only
Lunesta (eszopiclone) is used to treat insomnia in people over the age of 18. This medication can help you fall asleep faster and wake up fewer times during the night. Lunesta (eszopiclone) belongs to a drug class called sedative-hypnotics, and it's a controlled substance so there are restrictions on how it can be filled and refilled at the pharmacy. You typically only need to take a dose right before bedtime, but it can cause a headache or leave a bad taste in your mouth as a side effect.
Summary for Benzodiazepine
Prescription only
Flurazepam is used to treat sleeping problems (insomnia). It's a controlled substance because it has a risk for becoming habit-forming. The brand name Dalmane has been discontinued, but it's still available as generic versions. Side effects of the medication include headache and upset stomach.