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Quviviq vs. Lunesta

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Quviviq

(daridorexant)

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Lunesta

(eszopiclone)

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Summary for Quviviq

Prescription only

Quviviq (daridorexant) is an orexin antagonist that's used as a sleeping pill to help adults fall and stay asleep. It's available as a tablet that you take once every night, about 30 minutes before bedtime. You should take Quviviq (daridorexant) only if you can get at least 7 hours of sleep before waking up the next day. This medication might cause side effects like headache, daytime sleepiness, and dizziness. It's a schedule IV controlled substance because it has a risk for misuse.

Indications for Quviviq

  • Trouble falling or staying asleep (insomnia)

Pros and Cons for Quviviq

Pros

Cons

  • Should only take if you plan to sleep for at least 7 hours (otherwise you could feel overly sleepy or groggy during the daytime)
  • Hasn't been studied in children
  • Brand name only

Common Side Effects for Quviviq

  • Headache (up to 7%)
  • Sleepiness or fatigue (up to 6%)

Warnings for Quviviq

  • Daytime sleepiness
  • Suicidal thoughts and behaviors or worsening depression
  • Sleep paralysis, hallucinations, and cataplexy-like symptoms
  • Abnormal sleep behaviors
  • Caution in people with breathing problems

Summary for Lunesta

Prescription only

Lunesta (eszopiclone) is used to treat insomnia in people over the age of 18. This medication can help you fall asleep faster and wake up fewer times during the night. Lunesta (eszopiclone) belongs to a drug class called sedative-hypnotics, and it's a controlled substance so there are restrictions on how it can be filled and refilled at the pharmacy. You typically only need to take a dose right before bedtime, but it can cause a headache or leave a bad taste in your mouth as a side effect.

Indications for Lunesta

  • Insomnia (trouble falling or staying asleep)

Pros and Cons for Lunesta

Pros

  • Available as a lower-cost generic
  • Can help you fall asleep and stay asleep
  • Fewer side effects and less addicting than some other sleep medications

Cons

  • Can cause sedation, dizziness, and poor coordination the next day, especially at higher doses
  • Can lead to rebound insomnia after stopping the medication, especially if you've taken it for a long time
  • Risk of abnormal sleep behaviors, such as sleepwalking or sleep driving

Common Side Effects for Lunesta

Warnings for Lunesta

  • Abnormal sleep behaviors
  • Poor mental alertness
  • Behavior changes and abnormal thinking
  • Severe allergic reactions
  • Follow up with provider to check for other reasons for insomnia
  • Withdrawal
  • Use with caution in older adults and people with certain health conditions

Prices with our coupons for Quviviq vs. Lunesta

Price Card Drug Icon
Quviviq30 tablets / 50mg
$135.00$621.06
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Price Card Drug Icon
Eszopiclone30 tablets / 3mg
$12.67$232.78
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