Compare
Quviviq vs. Trazodone

Quviviq (daridorexant) is an orexin antagonist that's used as a sleeping pill to help adults fall and stay asleep. It's available as a tablet that you take once every night, about 30 minutes before bedtime. You should take Quviviq (daridorexant) only if you can get at least 7 hours of sleep before waking up the next day. This medication might cause side effects like headache, daytime sleepiness, and dizziness. It's a schedule IV controlled substance because it has a risk for misuse.

• Trouble falling or staying asleep (insomnia)

• Headache (up to 7%)
• Sleepiness or fatigue (up to 6%)

• Daytime sleepiness
• Suicidal thoughts and behaviors or worsening depression
• Sleep paralysis, hallucinations, and cataplexy-like symptoms
• Abnormal sleep behaviors
• Caution in people with breathing problems

Trazodone is an atypical antidepressant. It's FDA-approved to treat depression in adults, but it isn't a first-choice option. In addition, trazodone is sometimes prescribed off-label for difficulty sleeping (insomnia). This medication is taken by mouth, typically once or a few times a day, depending on your condition. Common side effects of this medication include sleepiness, dry mouth, and dizziness. Brand name Desyrel has been discontinued.

• Major depressive disorder (MDD)

• Sleepiness (up to 41%)
• Dry mouth (up to 34%)
• Dizziness or lightheadedness (up to 28%)
• Headache (up to 20%)
• Blurred vision (up to 15%)
• Nausea or vomiting (up to 13%)

• Worsening depression, suicidal thoughts, and unusual behavior
• Serotonin syndrome
• Life-threatening abnormal heart rhythm (QT prolongation)
• Difficulty concentrating and extreme sleepiness
• Dizziness from lower blood pressure
• Risk of bleeding
• Prolonged and painful erection
• Glaucoma
• Low blood sodium levels
• Withdrawal