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Orexin Receptor Antagonists

Orexin receptor antagonists are used to treat insomnia. They inhibit the effect of orexin, a neurotransmitter, in the brain. This works because orexin is involved in keeping you awake, and blocking it can help you fall asleep more easily.

Why are orexin receptor antagonists prescribed?

Insomnia (100%)

How are these percentages calculated?

Key takeaways

Orexin receptor antagonists are used to treat insomnia. These medications work by blocking the action of orexin, a chemical in your brain that helps regulate wakefulness and arousal. Orexin receptor antagonists are available as oral pills. Examples include Quviviq (daridorexant), Belsomra (suvorexant), and Dayvigo (lemborexant).

Prices for popular Orexin Receptor Antagonists medications

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Dayvigo

as low as$135

Dayvigo (lemborexant) CIV is used to treat insomnia (trouble falling or staying asleep) in adults.

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Quviviq

as low as$0

Quviviq (daridorexant) is a prescription medicine for adults who have trouble falling asleep or staying asleep (insomnia). There are currently no generic alternatives for Quviviq. It is covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

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Belsomra

as low as$462

Belsomra (suvorexant) is used to treat insomnia. Belsomra is an orexin receptor antagonist which works by inhibiting the neurotransmitter orexin, which is involved in wakefulness. The most common form of belsomra is a 10mg tablet. It is also available as a 5mg, 15mg, and 20mg tablet. There are currently no generic alternatives for belsomra. It is covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

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Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.