Key takeaways:
The starting Dayvigo (lemborexant) dosage for adults is 5 mg by mouth immediately before bed. If needed, your prescriber can raise your dose to a maximum of 10 mg per night.
Don’t take Dayvigo unless you have at least 7 hours to devote to sleep. Waking up earlier than this can cause excessive drowsiness.
If you have liver disease, you may need to take a lower Dayvigo dose or avoid it altogether. You may also need to take an adjusted dose or avoid Dayvigo if you take other medications that interact with it.
There are ways to save on Dayvigo. GoodRx can help you access Dayvigo at an exclusive cash price of $135 per month. A manufacturer savings card and patient assistance program are also available.
Insomnia is a health condition that makes it hard to fall asleep, stay asleep, or both. Some of the best insomnia treatments include lifestyle changes and cognitive behavioral therapy. But when these options aren’t enough, your healthcare team may recommend trying a sleep medication.
Dayvigo (lemborexant) is one of several prescription sleep medications. It works by blocking the activity of orexin, a chemical in your brain that tells you to wake up.
To get the most out of Dayvigo, you’ll want to make sure you’re taking it correctly. This includes taking your dose right before bed and devoting at least 7 hours to sleep. But is there anything else you should know about Dayvigo dosages?
Good to know: Dayvigo is FDA-approved for adults only. This medication hasn’t been studied for safety or effectiveness in children under age 18. So there are no recommended Dayvigo dosages for kids.
What’s the typical Dayvigo dosage for adults?
Dayvigo comes as 5 mg and 10 mg oral tablets. The recommended starting Dayvigo dosage for adults is 5 mg by mouth right before going to bed. If this doesn’t work well enough, your prescriber may raise your dose to 10 mg. This is the maximum Dayvigo dose.
Don’t take more than one Dayvigo tablet per night (even if it seems like the medication isn’t working). And make sure you can devote at least 7 hours to sleep after taking the medication. Trying to get up earlier than this can cause excessive drowsiness.
It’s best to take Dayvigo on an empty stomach. It may take the medication longer to start working if you take it with food.
Are there any Dayvigo dosage adjustments for health conditions?
Your liver breaks down Dayvigo using certain enzymes (proteins). Because of this, you may need to take a lower dose or avoid the medication if you have a history of liver problems. You may also need to take a different dosage or avoid Dayvigo if you take certain medications that interact with it.
Dayvigo dosage for people with liver problems
If you have moderate liver disease, it’s recommended to take no more than 5 mg of Dayvigo per night. If you have severe liver disease, you shouldn’t take Dayvigo at all. Your prescriber will let you know if your dosage needs to be adjusted.
Your liver is responsible for breaking down Dayvigo. But if your liver isn’t working correctly, it can cause Dayvigo to build up in your system. This can raise your risk of side effects, such as next-day drowsiness.
Dosage for people taking medications that interact with Dayvigo
There are many medications that interact with Dayvigo. Some medications can raise your risk of Dayvigo side effects. Others can make Dayvigo less effective.
Certain interactions can be managed by taking a lower Dayvigo dosage of 5 mg per night. But sometimes, you may need to avoid the combination altogether. The table below provides examples of Dayvigo interactions and how they’re usually managed.
| Take a lower 5 mg Dayvigo dose | Avoid combining with Dayvigo | |
|---|---|---|
| Example interactions |
|
|
This isn’t a full list of all Dayvigo interactions. Share your medication list with your prescriber and pharmacist so they can check for interactions. Be sure to include prescription and over-the-counter medications, as well as any supplements you take.
Is Dayvigo a controlled substance? Read pharmacists’ answers to this and other frequently asked questions about Dayvigo (lemborexant).
Comparing options: Dayvigo is one of several sleep medications available. Here’s a guide to prescription and over-the-counter sleep aids.
What to expect: Learn about notable Dayvigo side effects — from headaches to unusual dreams — and how to manage them.
What happens if you miss a dose of Dayvigo?
If you miss your usual dose time and still have at least 7 hours to devote to sleep, take Dayvigo as soon as you can. But don’t take Dayvigo if you have less than 7 hours before you need to wake up.
Some healthcare professionals may suggest taking Dayvigo only as needed. Others may recommend taking the medication every night on a schedule. Be sure to follow your prescriber’s instructions.
What should you do if you take too much Dayvigo?
Taking too much Dayvigo raises your risk of side effects. These include excessive drowsiness, daytime impairment, and headaches. Depending on how much Dayvigo you took, side effects could be severe. And drowsiness could linger for several days.
If you took too much Dayvigo, contact your prescriber right away for guidance. You can also contact Poison Control online or by calling 1-800-222-1222. If you’re experiencing any symptoms that seem severe or life-threatening, call 911 or go to the nearest ER.
Good to know: Dayvigo is a controlled substance. It carries a risk for misuse and dependence. Taking Dayvigo as prescribed helps to lower your risk of these serious side effects.
How to save
There are ways to save on Dayvigo, which is available as a brand-name medication. GoodRx can help you navigate between GoodRx coupons, copay savings cards, and patient assistance programs to save money on your prescription.
Save with GoodRx: Anyone with a valid prescription, regardless of insurance status, can use GoodRx to purchase a 30-day supply of Dayvigo at an exclusive cash price of $135.
Save with a copay savings card: If you have commercial insurance, you may be eligible to pay as little as $10 per month for Dayvigo using a savings card from the manufacturer.
Save with a patient assistance program: If you’re uninsured or underinsured, you may be eligible for Dayvigo’s patient assistance program, which offers the medication free of charge.
The bottom line
The starting Dayvigo (lemborexant) dosage for adults is 5 mg by mouth immediately before bedtime. If needed, the dosage can be raised to a maximum of 10 mg per night. It’s best to take Dayvigo on an empty stomach.
Don’t take more than 1 tablet per night. And don’t take Dayvigo unless you have at least 7 hours to devote to sleep. Trying to wake up earlier than this can cause excessive drowsiness.
People with liver problems may need to take a lower Dayvigo dosage or avoid the medication. This is also the case for people taking medications that interact with Dayvigo. Your prescriber should tell you if you need any Dayvigo dosage adjustments.
Why trust our experts?
References
Ardeljan, A. D., et al. (2023). Lemborexant. StatPearls.
Eisai. (2025). Dayvigo- lemborexant tablet, film coated [package insert].
Poison Control. (n.d.). Get help online or by phone.
U.S. Food and Drug Administration. (2025). For healthcare professionals | FDA’s examples of drugs that interact with CYP enzymes and transporter systems.
