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Dayvigo vs. Melatonin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Dayvigo

(lemborexant)

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Melatonin

 

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Summary for Dayvigo

Prescription only

Dayvigo (lemborexant) CIV is a medication that's used to help adults who have trouble falling or staying asleep (insomnia). This sleep medication belongs to the drug class called orexin receptor antagonists. The typical dosage for the Dayvigo (lemborexant) tablets is 5 mg or 10 mg that's taken by mouth right before bedtime. You should take the medication only if you know you can get at least 7 hours of sleep before you need to wake up the next day. Common side effects include sleepiness and headache. Dayvigo (lemborexant) is a controlled substance because it has a risk for misuse.

Indications for Dayvigo

  • Trouble falling asleep or staying asleep (insomnia)

Pros and Cons for Dayvigo

Pros

  • Can help you fall asleep faster and stay asleep longer
  • Taken right before you plan to go to sleep
  • Not likely to cause withdrawal if you stop taking the medication suddenly

Cons

  • Can cause daytime sleepiness, especially if you get less than the recommended 7 hours of sleep after you take the medication
  • Not recommended for people with severe liver problems
  • Not known if it's safe or if it works well for children

Common Side Effects for Dayvigo

  • Feeling sleepy or tired (up to 10%)
  • Headache (up to 6%)
  • Nightmares or unusual dreams (up to 2%)

Warnings for Dayvigo

  • Daytime sleepiness
  • Suicidal thoughts and behaviors or worsening depression
  • Sleep paralysis, hallucinations, and cataplexy-like symptoms
  • Abnormal sleep behaviors
  • Use with caution in people with breathing problems

Summary for Melatonin

Over-the-counter

Melatonin is a supplement that's taken to help with sleep problems due to conditions like insomnia or jet lag. It's available over-the-counter and comes in many different formulations, including oral pills and sprays, skin patches, and topical creams. Various melatonin products have different instructions and age recommendations, so speak with your provider or pharmacist to check if it's safe for children. Melatonin is pretty well tolerated, but possible side effects include daytime sleepiness, headaches, and nausea.

Indications for Melatonin

Pros and Cons for Melatonin

Pros

  • Generally well tolerated with very few side effects
  • Usually not habit-forming like some other sleep aids
  • Available over the counter (OTC) in many different dosage forms and strengths
  • Available as a lower-cost generic

Cons

Common Side Effects for Melatonin

Warnings for Melatonin

  • Worsening of certain medical conditions
  • Overdose in children
  • Interactions with other medications

Prices with our coupons for Dayvigo vs. Melatonin

Price Card Drug Icon
Dayvigo30 tablets / 10mg
$135.00$431.30
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Price Card Drug Icon
Melatonin30 tablets / 3mg
$6.53$8.10
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