Key takeaways
Zaleplon (Sonata) and estazolam (formerly branded as Prosom) are both medications used to treat insomnia, but they have some key differences. Zaleplon is a non-benzodiazepine sedative-hypnotic that helps you fall asleep quickly but doesn't help you stay asleep. Estazolam , on the other hand, is a benzodiazepine that helps you both fall asleep and stay asleep. Zaleplon is only recommended for short-term use (up to 30 days) and is available as a generic. Estazolam is also meant for short-term use and is only available as a generic since the brand name is no longer on the market. Both medications can be habit-forming and may cause dependence, but estazolam has a higher risk of causing drowsiness and affecting your concentration the next day. Additionally, estazolam is not recommended for older adults due to the increased risk of falls, while zaleplon may cause fewer next-day drowsiness issues. Both medications can cause unusual sleep behaviors like sleep-walking or sleep-driving, and you should avoid alcohol and other sedatives while taking them.
