Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Estazolam (Prosom) and butabarbital (Butisol) are both medications used to help with sleep, but they belong to different medication classes. Estazolam is a benzodiazepine, while butabarbital is a barbiturate. Both medications are controlled substances, with estazolam being a Schedule IV and butabarbital a Schedule III, indicating different levels of potential for misuse. Estazolam is still available as a generic medication, but butabarbital has been discontinued and is no longer available in the U.S. Estazolam is specifically FDA-approved for the short-term treatment of insomnia, whereas butabarbital was used for sleep but is not a first-choice treatment. Estazolam is taken as a tablet by mouth at bedtime, while butabarbital was known for its fast-acting properties. Common side effects of estazolam include sleepiness, headache, and dizziness, and it can cause unusual sleep behaviors. Butabarbital, on the other hand, was noted for its potential to be habit-forming.
Estazolam (Prosom)
Butisol (butabarbital)
Estazolam (Prosom)
Butisol (butabarbital)
Summary of Estazolam vs. Butisol
Summary for Benzodiazepine
Prescription only
Estazolam (Prosom) is a sleeping pill that can help adults with insomnia fall asleep and stay asleep. It's a benzodiazepine medication that's not a first-choice treatment option for trouble sleeping, and it's only meant for short-term use since it can be habit-forming. It comes as a tablet that you take by mouth right before you get into bed. It's only available as a generic since the brand-name medication, Prosom, is no longer on the market. In addition to causing sleepiness, other common side effects can include headache, weakness, and nervousness.
Summary for Barbiturate
Butisol (butabarbital) is a fast-acting sleep medication. It's not a first choice treatment option and has been discontinued. Both brand and generic options are no longer available in the U.S.