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Dayvigo vs. Lunesta

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Dayvigo

(lemborexant)

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Lunesta

(eszopiclone)

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Summary for Dayvigo

Prescription only

Dayvigo (lemborexant) CIV is a medication that's used to help adults who have trouble falling or staying asleep (insomnia). This sleep medication belongs to the drug class called orexin receptor antagonists. The typical dosage for the Dayvigo (lemborexant) tablets is 5 mg or 10 mg that's taken by mouth right before bedtime. You should take the medication only if you know you can get at least 7 hours of sleep before you need to wake up the next day. Common side effects include sleepiness and headache. Dayvigo (lemborexant) is a controlled substance because it has a risk for misuse.

Indications for Dayvigo

  • Trouble falling asleep or staying asleep (insomnia)

Pros and Cons for Dayvigo

Pros

  • Can help you fall asleep faster and stay asleep longer
  • Taken right before you plan to go to sleep
  • Not likely to cause withdrawal if you stop taking the medication suddenly

Cons

  • Can cause daytime sleepiness, especially if you get less than the recommended 7 hours of sleep after you take the medication
  • Not recommended for people with severe liver problems
  • Not known if it's safe or if it works well for children

Common Side Effects for Dayvigo

  • Feeling sleepy or tired (up to 10%)
  • Headache (up to 6%)
  • Nightmares or unusual dreams (up to 2%)

Warnings for Dayvigo

  • Daytime sleepiness
  • Suicidal thoughts and behaviors or worsening depression
  • Sleep paralysis, hallucinations, and cataplexy-like symptoms
  • Abnormal sleep behaviors
  • Use with caution in people with breathing problems

Summary for Lunesta

Prescription only

Lunesta (eszopiclone) is used to treat insomnia in people over the age of 18. This medication can help you fall asleep faster and wake up fewer times during the night. Lunesta (eszopiclone) belongs to a drug class called sedative-hypnotics, and it's a controlled substance so there are restrictions on how it can be filled and refilled at the pharmacy. You typically only need to take a dose right before bedtime, but it can cause a headache or leave a bad taste in your mouth as a side effect.

Indications for Lunesta

  • Insomnia (trouble falling or staying asleep)

Pros and Cons for Lunesta

Pros

  • Available as a lower-cost generic
  • Can help you fall asleep and stay asleep
  • Fewer side effects and less addicting than some other sleep medications

Cons

  • Can cause sedation, dizziness, and poor coordination the next day, especially at higher doses
  • Can lead to rebound insomnia after stopping the medication, especially if you've taken it for a long time
  • Risk of abnormal sleep behaviors, such as sleepwalking or sleep driving

Common Side Effects for Lunesta

Warnings for Lunesta

  • Abnormal sleep behaviors
  • Poor mental alertness
  • Behavior changes and abnormal thinking
  • Severe allergic reactions
  • Follow up with provider to check for other reasons for insomnia
  • Withdrawal
  • Use with caution in older adults and people with certain health conditions

Prices with our coupons for Dayvigo vs. Lunesta

Price Card Drug Icon
Dayvigo30 tablets / 10mg
$135.00$431.30
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Price Card Drug Icon
Eszopiclone30 tablets / 3mg
$12.67$232.78
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