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Compare Buspar vs. Ativan

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Buspirone and lorazepam (brand names Ativan, Loreev XR) are both used to treat anxiety, but they have some key differences. Buspirone is an antianxiety medication that is not a controlled substance and is typically taken twice daily. It takes a few weeks to start working and is not for quick relief of anxiety. Common side effects include dizziness, nausea, and headache. Lorazepam, on the other hand, is a benzodiazepine and a Schedule IV controlled substance, meaning it has a higher risk of dependence and misuse. It works faster than buspirone, often within 30 minutes, and is used for short-term relief of anxiety. Lorazepam can cause sleepiness and dizziness and has a risk of withdrawal symptoms if stopped suddenly. While buspirone is generally considered safer for long-term use, lorazepam is more effective for immediate anxiety relief.

  • Buspirone
    Lorazepam (Ativan)
  • Buspirone
    Lorazepam (Ativan)

  • Summary of Buspar vs. Ativan

    Summary for Antianxiety
    Prescription only

    Buspirone is used to relieve anxiety, but it's not a first-choice medication. Your provider might consider adding on buspirone if your anxiety symptoms aren't well-controlled by other medications. It's taken by mouth, typically twice daily. Unlike some other anti-anxiety medications, it's not a controlled substance. Some common side effects of buspirone include dizziness, nausea, headache, and nervousness. The brand name Buspar is no longer available.

    Summary for Benzodiazepine
    Prescription only

    Lorazepam (Ativan) is a benzodiazepine used for short-term treatment of anxiety. The oral tablets and solution are taken by mouth, typically 1 to 3 times daily, depending on the formulation. Lorazepam is also available as an injectable medication that's given by healthcare professionals in a hospital setting to control seizures. Sleepiness and dizziness are the most common side effects of lorazepam (Ativan).

  • Indications of Buspar vs. Ativan

    Indications for
    •Anxiety
    Indications for
    •Anxiety disorders
    •Anxiety associated with depressive symptoms
    •Short-term relief of anxiety
    •Seizures lasting longer than 5 minutes - injection only
    •Surgery-related anxiety, usually given shortly before anesthesia - injection only

  • Pros and Cons of Buspar vs. Ativan

    Pros and Const for Antianxiety
    Pros
    •Much lower risk for dependency and withdrawal symptoms than other anti-anxiety medications
    •Taken by mouth
    •Can be taken by children as young as 6 years old
    •Can cut tablets if needed
    •Available as a lower-cost generic
    Cons
    •Not a first-choice treatment option for anxiety
    •Not for quick relief of anxiety or panic attacks
    •Can take a few weeks to fully kick in
    •Typically taken twice a day
    •Interacts with many medications and grapefruit juice
    Pros and Const for Benzodiazepine
    Pros
    •Taken by mouth
    •Might start to work within 30 minutes to manage anxiety symptoms
    •Available as oral solution, good option for those who can't swallow tablets
    •Some forms available as a lower-cost generic
    Cons
    •Short-term use only because risk of dependence and memory problems
    •Can drowsiness, and dizziness
    •Can cause withdrawal symptoms if stopped suddenly
    •Can't take with alcohol

  • Common Side Effects of Buspar vs. Ativan

    Common Side Effects for
    •Dizziness (12%)
    •Drowsiness (10%)
    •Nausea (8%)
    •Headache (6%)
    •Nervousness (5%)
    Common Side Effects for
    •Sleepiness (16%)
    •Dizziness (7%)
    •Weakness (4%)
    •Unsteadiness (3%)

  • Warnings of Buspar vs. Ativan

    Common Side Effects for
    •Serotonin syndrome
    •Effect on driving and concentration
    •Withdrawal symptoms from stopping other anxiety medications
    •Don't take with monoamine oxidase inhibitors (MAOIs)
    Common Side Effects for
    •Sedation and difficulty breathing
    •Misuse, dependence, and withdrawal
    •Depression and suicidal thoughts or behaviors
    •Effect on driving and concentration
    •Trouble breathing
    •Risk of agitation and restlessness
    •Harm to babies
    •Serious allergic reaction (Loreev XR only)

  • Prices with our coupons for Buspar vs. Ativan

    Learn more about Buspirone
    Learn more about Lorazepam

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