Key takeaways
Hydroxyzine (Vistaril) and buspirone (Buspar) are both used to treat anxiety, but they have some key differences. Hydroxyzine is an antihistamine that can also help with itching and allergies, while buspirone is specifically an antianxiety medication. Hydroxyzine works quickly, often within 15 to 30 minutes, but it can cause drowsiness and is not recommended for long-term use. In contrast, buspirone takes about 2 to 4 weeks to show effects and is taken twice daily. Buspirone has a lower risk of dependency and withdrawal symptoms compared to other anxiety medications, but it can cause dizziness and nausea. Hydroxyzine is available in both pill and liquid forms, while buspirone is only available as a pill.
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