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NSAID Cough and Cold Combinations

NSAIDs (Non-steroidal anti-inflammatory medications) are combined with other active ingredients like diphenhydramine (Benadryl), and dextromethorphan to relieve cough, cold, allergy, and insomnia symptoms along with treating pain and fever.

Why are nsaid cough and cold combinations prescribed?

  1. Pain (30%)
  2. Nasal Congestion (30%)
  3. Fever (30%)
  4. Allergic Rhinitis (9%)
  5. Cold Symptoms (0%)
  6. Cough (0%)
  7. Insomnia (0%)

Key takeaways

Nonsteroidal anti-inflammatory drug (NSAID) cough and cold combinations are used to treat symptoms like runny nose and sinus pain or congestion that are due to the common cold or allergies. Certain medications in this class can also be used for occasional sleeping troubles that are accompanied by muscle aches and pain. These medications work by combining an NSAID with other ingredients like decongestants or antihistamines to reduce inflammation, relieve pain, and clear nasal congestion. They come in different forms, primarily as oral tablets or capsules. Examples include ibuprofen / pseudoephedrine (Advil Cold and Sinus), ibuprofen / diphenhydramine (Advil PM, Motrin PM), and aspirin / chlorpheniramine / phenylephrine (Alka Seltzer Plus Cold). You can choose the combination that best fits your symptoms.

Prices for popular NSAID Cough and Cold Combinations medications
Viewing 10 of 10 medications
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Advil Cold and Sinus (ibuprofen / pseudoephedrine)

as low as$7
IBUPROFEN; PSEUDOEPHEDRINE treats the symptoms of the common cold, allergies, or flu. It works by reducing pain and fever. It also decreases a runny or stuffy nose. It is a combination of an NSAID and a decongestant.
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Advil Allergy Sinus

as low as$31
CHLORPHENIRAMINE; IBUPROFEN; PSEUDOEPHEDRINE treats the symptoms of the common cold, allergies, or flu. It works by reducing pain, fever, and red, itchy eyes. It also decreases a runny or stuffy nose. It is a combination of an NSAID, an antihistamine, and a decongestant.
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Advil PM (ibuprofen PM)

as low as$9
DIPHENHYDRAMINE; IBUPROFEN treats pain and helps you get to sleep faster. It is a combination of an antihistamine and NSAID.
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Advil Allergy and Congestion

as low as$11
Advil Allergy And Congestion is only available as a brand name drug.
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Sudafed Pressure and Pain

as low as$14
Sudafed Pressure And Pain is part of the NSAID Cough and Cold Combinations class and treats Pain, Nasal Congestion and Fever. NSAIDs (Non-steroidal anti-inflammatory medications) are combined with other active ingredients like diphenhydramine (Benadryl), and dextromethorphan to relieve cough, cold, allergy, and insomnia symptoms along with treating pain and fever. Sudafed Pressure And Pain is only available as a brand name drug.
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Motrin PM (ibuprofen PM)

as low as$15
DIPHENHYDRAMINE; IBUPROFEN treats pain and helps you get to sleep faster. It is a combination of an antihistamine and NSAID.
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Advil Congestion

Advil Congestion is part of the NSAID Cough and Cold Combinations class and treats Pain, Nasal Congestion and Fever. NSAIDs (Non-steroidal anti-inflammatory medications) are combined with other active ingredients like diphenhydramine (Benadryl), and dextromethorphan to relieve cough, cold, allergy, and insomnia symptoms along with treating pain and fever. Advil Congestion is only available as a brand name drug.
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Alka-Seltzer Plus Cold

Alka-Seltzer Plus Cold is part of the NSAID Cough and Cold Combinations class and treats Cold Symptoms and Fever. NSAIDs (Non-steroidal anti-inflammatory medications) are combined with other active ingredients like diphenhydramine (Benadryl), and dextromethorphan to relieve cough, cold, allergy, and insomnia symptoms along with treating pain and fever. Alka-Seltzer Plus Cold is only available as a brand name drug.
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Alka-Seltzer Plus Cold and Cough

Alka-Seltzer Plus Cold And Cough is part of the NSAID Cough and Cold Combinations class and treats Cold Symptoms and Cough. NSAIDs (Non-steroidal anti-inflammatory medications) are combined with other active ingredients like diphenhydramine (Benadryl), and dextromethorphan to relieve cough, cold, allergy, and insomnia symptoms along with treating pain and fever. Alka-Seltzer Plus Cold And Cough is only available as a brand name drug.
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aspirin / chlorpheniramine / phenylephrine

Aspirin/Chlorpheniramine/Phenylephrine is part of the NSAID Cough and Cold Combinations class and treats Nasal Congestion, Cold Symptoms and Fever. NSAIDs (Non-steroidal anti-inflammatory medications) are combined with other active ingredients like diphenhydramine (Benadryl), and dextromethorphan to relieve cough, cold, allergy, and insomnia symptoms along with treating pain and fever. Aspirin/Chlorpheniramine/Phenylephrine is only available as a generic drug.
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Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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