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Compare Mucinex Sinus Max Pressure and Pain vs. Dayquil

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Acetaminophen/phenylephrine (Sudafed PE Pressure Plus Pain) and acetaminophen/dextromethorphan/phenylephrine (Dayquil Cold and Flu) are both over-the-counter medications used to relieve symptoms of the common cold, such as nasal congestion, headache, and minor aches and pains. They both contain acetaminophen, which helps relieve pain and reduce fever, and phenylephrine, which acts as a decongestant. However, Dayquil Cold and Flu also includes dextromethorphan, a cough suppressant, which is not in Sudafed PE Pressure Plus Pain. Sudafed PE Pressure Plus Pain is available as caplets, while Dayquil Cold and Flu comes in both pill and liquid forms. Both medications are taken every 4 hours, but Dayquil Cold and Flu has a maximum of 8 doses per 24-hour period, while Sudafed PE Pressure Plus Pain allows up to 10 caplets. Both medications may cause nervousness. Both medications contain acetaminophen, so be careful not to take other over-the-counter products that also contain acetaminophen. Taking too acetaminophen can harm your liver.

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