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Compare Triazolam vs. Ambien

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Triazolam (Halcion) and zolpidem (Ambien) are both medications used to treat insomnia, but they belong to different drug classes and have distinct characteristics. Triazolam is a benzodiazepine that works by relaxing your nervous system, while zolpidem is a GABA A receptor positive modulator that slows down brain activity to help you sleep. Triazolam is typically used for short-term treatment (7 to 10 days) and is known for its quick onset and short duration, making it effective for falling asleep but not necessarily staying asleep. On the other hand, zolpidem can be used for both falling asleep and staying asleep, with various forms available, including immediate-release and extended-release tablets, as well as sublingual tablets. Both medications carry risks of misuse, dependence, and withdrawal, but zolpidem has additional risks of abnormal sleep behaviors like sleepwalking and sleep driving. Triazolam is not recommended during pregnancy due to potential harm to the baby, while the safety of zolpidem during pregnancy is not well established. Both medications should be taken exactly as prescribed to minimize risks and side effects.

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