Key takeaways
Temazepam (Restoril) and Silenor (doxepin) are both used to treat insomnia, but they have some key differences. Temazepam is a benzodiazepine capsule that works by slowing down brain activity, making it easier to fall and stay asleep. It is a controlled substance (Schedule IV) due to its potential for misuse, addiction, and withdrawal symptoms. Silenor, on the other hand, is a tricyclic antidepressant tablet that blocks histamine receptors to help you stay asleep. Unlike temazepam, Silenor is not addictive and is not a controlled substance. Temazepam is typically used for short periods (7 to 10 days) and can cause a "hangover" effect the next day, while Silenor can be used longer without the risk of dependency. Both medications are available in generic forms, but Silenor must be taken on an empty stomach, whereas temazepam can be taken with or without food.
