Key takeaways
Ramelteon (Rozerem) and temazepam (Restoril) are both used to treat insomnia, but they work in different ways and have different risks. Ramelteon is a melatonin receptor agonist that mimics the natural hormone melatonin to help you fall asleep. It is not a controlled substance and is not known to be habit-forming. On the other hand, temazepam is a benzodiazepine that works by slowing down brain activity. It is a Schedule IV controlled substance due to its risks of misuse, addiction, and withdrawal symptoms if stopped suddenly. Temazepam is only recommended for short-term use and can cause a "hangover" feeling the next day, whereas ramelteon is not associated with this effect. Both medications are available in generic forms, but temazepam requires close monitoring due to its potential for dependence and serious side effects. Ramelteon is typically taken 30 minutes before bedtime on an empty stomach, while temazepam can be taken with or without food.
