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Nasal Congestion Medications

Find prices and information on Nasal Congestion medications.

Read our guide toNasal Congestion

Key takeaways

Medications for nasal congestion are used to treat a stuffy nose caused by allergies and upper respiratory infections, such as the common cold and sinus infections. These work by reducing nasal inflammation and shrinking swollen nasal tissues. Common classes include intranasal corticosteroids and alpha-1 agonists. Intranasal corticosteroids, such as fluticasone propionate (Flonase) and mometasone (Nasonex), are available as nasal sprays. Alpha-1 agonists, such as pseudoephedrine (Sudafed) and oxymetazoline (Afrin), come in oral forms and as nasal sprays. These options provide different ways to help relieve your nasal congestion effectively.

Prices for popular Nasal Congestion medications
Viewing 25 of 95 medications
View otherCorticosteroids
Triamcinolone (Kenalog) is an inexpensive drug used to reduce swelling and ulcers in the mouth. It helps treat and relieve mouth sores that are not caused by herpes. this drug is slightly more popular than comparable drugs. It is available in multiple brand and generic forms. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Fluticasone propionate (Cutivate) is an inexpensive drug used on the skin to reduce swelling, pain, and itching. It is slightly more popular than comparable drugs. It is available in brand and generic versions. Generic fluticasone propionate is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Promethazine dm is an inexpensive drug used to treat nasal congestion, allergic rhinitis, cold symptoms, and other conditions. It is more popular than comparable drugs. Promethazine is only available as a generic drug; all brands have been discontinued. Generic promethazine dm is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
BROMPHENIRAMINE; PSEUDOEPHEDRINE; DEXTROMETHORPHAN treats the symptoms of the common cold, allergies, or flu. It works by reducing red, itchy eyes and cough. It also decreases a runny or stuffy nose. It is a combination of an antihistamine, a cough suppressant, and a decongestant.
PHENYLEPHRINE treats a runny or stuffy nose. It may also be used to treat sinus congestion and pressure. It works by decreasing swelling in the nose, making it easier to breathe. It belongs to a group of medications called decongestants.
Sudafed PE Pressure And Pain is part of the Acetaminophen Combinations class and treats Pain, Nasal Congestion and Fever. Acetaminophen is combined with other active ingredients like diphenhydramine and dextromethorphan to relieve cough, cold, allergy, and insomnia symptoms along with treating pain, menstrual pain, and fever. Sudafed PE Pressure And Pain is only available as a brand name drug.
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Histex-Ac

as low as$4
Histex-Ac is part of the Antihistamine / Opioid / Alpha-1 Agonist Combinations class and treats Nasal Congestion, Allergic Rhinitis, Cold Symptoms and other conditions. Antihistamine / opioid / alpha-1 agonist combinations are used to treat cough, nasal congestion, cold symptoms, and allergic rhinitis. They work by suppressing cough, relieving nasal congestion, and reducing cold symptoms. Histex-Ac is only available as a brand name drug.
PHENYLEPHRINE treats a runny or stuffy nose. It may also be used to treat sinus congestion and pressure. It works by decreasing swelling in the nose, making it easier to breathe. It belongs to a group of medications called decongestants.
BROMPHENIRAMINE; DEXTROMETHORPHAN; PHENYLEPHRINE treats the symptoms of the common cold, allergies, or flu. It works by reducing red, itchy eyes and cough. It also decreases a runny or stuffy nose. It is a combination of an antihistamine, a cough suppressant, and a decongestant.
OXYMETAZOLINE treats a runny or stuffy nose. It may also be used to treat sinus congestion and pressure. It is often used for a short period of time. It works by decreasing swelling in the nose, making it easier to breathe. It belongs to a group of medications called decongestants.
CHLORPHENIRAMINE; PHENYLEPHRINE treats the symptoms of the common cold, allergies, or flu. It works by reducing red, itchy eyes and a runny or stuffy nose. It is a combination of an antihistamine and a decongestant.
ACETAMINOPHEN; CHLORPHENIRAMINE; PHENYLEPHRINE treats the symptoms of the common cold, allergies, or flu. It works by reducing pain, fever, and red, itchy eyes. It also decreases a runny or stuffy nose. It is a combination of acetaminophen, an antihistamine, and a decongestant.
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rynex DM

as low as$5
BROMPHENIRAMINE; DEXTROMETHORPHAN; PHENYLEPHRINE treats the symptoms of the common cold, allergies, or flu. It works by reducing red, itchy eyes and cough. It also decreases a runny or stuffy nose. It is a combination of an antihistamine, a cough suppressant, and a decongestant.
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Dayquil

as low as$6
Dayquil is part of the Acetaminophen Combinations class and treats Pain, Nasal Congestion, Cough and other conditions. Acetaminophen is combined with other active ingredients like diphenhydramine and dextromethorphan to relieve cough, cold, allergy, and insomnia symptoms along with treating pain, menstrual pain, and fever. Dayquil is only available as a brand name drug.
ACETAMINOPHEN; GUAIFENESIN; PHENYLEPHRINE treats the symptoms of the common cold, allergies, or flu. It works by reducing pain and fever. It also decreases a runny or stuffy nose and loosens mucus. It is a combination of acetaminophen, a decongestant, and an expectorant.
ACETAMINOPHEN; CHLORPHENIRAMINE; DEXTROMETHORPHAN; PHENYLEPHRINE treats the symptoms of the common cold, allergies, or flu. It works by reducing pain, fever, cough, and red, itchy eyes. It also decreases a runny or stuffy nose. It is a combination of acetaminophen, an antihistamine, a cough suppressant, and a decongestant.
Sudafed (pseudoephedrine) is an alpha agonist used to treat nasal congestion and sinus pressure. It works by restricting the blood vessels in the nose and sinuses. Sudafed doesn't require a prescription, but there are restrictions on its purchase and it is only available at the pharmacy counter. Generic pseudoephedrine is available, and Sudafed PE is another over-the-counter alternative with a different active ingredient (phenylephrine) that has no restrictions.
Tylenol + Cold + Flu + Cough Night is part of the Acetaminophen Combinations class and treats Pain, Nasal Congestion, Flu and other conditions. Acetaminophen is combined with other active ingredients like diphenhydramine and dextromethorphan to relieve cough, cold, allergy, and insomnia symptoms along with treating pain, menstrual pain, and fever. Tylenol + Cold + Flu + Cough Night is only available as a brand name drug.
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Zephrex-D

as low as$6
PSEUDOEPHEDRINE treats a runny or stuffy nose. It may also be used to treat sinus congestion and pressure. It works by decreasing swelling in the nose, making it easier to breathe. It belongs to a group of medications called decongestants.
PSEUDOEPHEDRINE; TRIPROLIDINE treats the symptoms of the common cold, allergies, or flu. It works by reducing red, itchy eyes and a runny or stuffy nose. It is a combination of an antihistamine and a decongestant.
GUAIFENESIN; PHENYLEPHRINE treats the symptoms of the common cold, allergies, or flu. It works by decreasing a runny or stuffy nose and loosening mucus. It is a combination of a decongestant and an expectorant.
ACETAMINOPHEN; GUAIFENESIN; PHENYLEPHRINE treats the symptoms of the common cold, allergies, or flu. It works by reducing pain and fever. It also decreases a runny or stuffy nose and loosens mucus. It is a combination of acetaminophen, a decongestant, and an expectorant.
Dexbrompheniramine/Phenylephrine is part of the Antihistamine / Alpha-1 Agonist Combinations class and treats Nasal Congestion. Antihistamine / alpha-1 agonist combinations are used to treat allergic rhinitis, nasal congestion, and cold symptoms. They work by shrinking blood vessels in the nose for congestion and by blocking histamine which causes the symptoms of stuffy nose, runny nose, itchy throat, and sneezing. Dexbrompheniramine/Phenylephrine is only available as a generic drug.
SODIUM CHLORIDE reduces swelling in the eye. It works by decreasing the amount of fluid in your eye, which reduces eye discomfort and irritation.
IBUPROFEN; PSEUDOEPHEDRINE treats the symptoms of the common cold, allergies, or flu. It works by reducing pain and fever. It also decreases a runny or stuffy nose. It is a combination of an NSAID and a decongestant.
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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