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Brompheniramine / Dextromethorphan / Phenylephrine Coupon - Brompheniramine / Dextromethorphan / Phenylephrine 2mg/10mg/5mg/10ml oral solution

brompheniramine / dextromethorphan / phenylephrine

Generic Rynex DM
Used for Nasal Congestion, Allergic Rhinitis, Cold Symptoms, Cough
Used for Nasal Congestion, Allergic Rhinitis, Cold Symptoms, Cough

Rynex DM is a combination of three medications: brompheniramine (an antihistamine), dextromethorphan (a cough suppressant), and phenylephrine (a decongestant). Rynex DM is an over-the-counter liquid medication for adults and children with allergy and common cold symptoms, such as cough, stuffy nose, and itchy or watery eyes. It's typically taken by mouth every 4 hours as needed for symptom relief. Possible side effects include drowsiness, restlessness, dizziness, and dry mouth.

Note: This combination medication can also be found as liquids under other brand names, including Endacof DM and Children's Dimetapp Cold and Cough.

Last reviewed on May 22, 2024
basics-icon

What is Rynex DM?

What is Rynex DM used for?

Short-term relief of symptoms from allergies and the common cold:

  • Cough from throat and lung irritation

  • Runny nose

  • Sneezing

  • Itchy or watery eyes

  • Itching of the nose or throat

  • Stuffy nose (nasal congestion)

How Rynex DM works

Rynex DM is a combination of three medications that work together to relieve symptoms caused by allergies and the common cold.

Drug Facts

Common BrandsRynex DM
Drug ClassAntihistamine / Cough suppressant / Decongestant
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityOver-the-counter
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Avg retail price
$3.870
GoodRx discount
$3.87
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What are the side effects of Rynex DM?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Other Side Effects

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Serotonin syndrome: fast heart rate, sweating, muscle stiffness or spasms, high fever, confusion

Source: DailyMed

The following side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Heart palpitations—rapid, pounding, or irregular heartbeat
  • Increase in blood pressure
  • Sudden eye pain or change in vision such as blurry vision, seeing halos around lights, vision loss
  • Trouble passing urine

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

pros-and-cons

Pros and cons of Rynex DM

thumbs-up

Pros

Convenient to take three medications in one liquid product

Starts working within 30 minutes to an hour

Can treat a wide variety of allergy and common cold symptoms

Available over the counter

thumbs-down

Cons

Might need to take every 4 hours for symptom relief

More difficult to customize the dose since it's a combination of three medications

Only available as a liquid

Not the best choice for people over 65 years old or people with glaucoma, breathing problems, stomach problems, or urinary problems

pharmacist-tips

Pharmacist tips for Rynex DM

pharmacist
  • You can take Rynex DM with or without food.

    • Use a medication dose cup or an oral syringe to measure your dose of Rynex DM. Don't use household spoons because they might not be accurate and using them might cause you to take the wrong dose.

      • Rynex DM can make you feel sleepy or dizzy during the day since it contains dextromethorphan (a cough suppressant) and brompheniramine (an antihistamine). Don't drive or do anything that requires a lot of attention or focus until you know how Rynex DM affects you.

        • Avoid drinking alcohol while you're taking Rynex DM. Alcohol can make you feel even sleepier or dizzier.

          • Stop taking Rynex DM and contact your healthcare team if you feel dizzy or nervous or if you have trouble sleeping. These might be side effects from the phenylephrine or other medications in Rynex DM. Your care team can give recommendations on how to lessen these side effects, such as taking the medication less often.

            • You should use Rynex DM to relieve cold or allergy symptoms for a short period of time only. Let a healthcare professional know if your symptoms worsen or last longer than a week. You might need other treatment to relieve your symptoms better.

              • Stop taking Rynex DM and tell your primary care provider if you start to have a fever, rash, or headache. These might be signs that you need more medical attention.

                • Don't start any new medications — especially other antihistamines, cough suppressants, or decongestants — while you're taking Rynex DM without talking to a healthcare professional first. Some medications can raise your risk for severe side effects, including extreme sleepiness, high blood pressure, fast heart rate, seizures, or hallucinations (seeing things that aren't real).

                  faqs

                  Frequently asked questions about Rynex DM

                  Is Rynex DM a controlled substance?
                  No, Rynex DM isn't a controlled substance. But Rynex DM contains dextromethorphan, which has a potential for misuse. When it's taken in large amounts, dextromethorphan can cause "out-of-body" sensations and a "high" feeling. At the same time, large amounts of dextromethorphan can cause serious and life-threatening side effects, such as seizures, heart rhythm problems, and panic. Because teens are at highest risk of misusing dextromethorphan and of its serious side effects, many states require you to be at least 18 years old to purchase medications containing dextromethorphan, including Rynex DM.
                  Is Rynex DM the same as Rynex?
                  "Rynex" is a line of branded products. Rynex DM is a brand-name medication containing brompheniramine (an antihistamine), dextromethorphan (a cough suppressant), and phenylephrine (a decongestant). Rynex PE contains brompheniramine and phenylephrine, and Rynex PSE contains brompheniramine and pseudoephedrine (a decongestant). These "Rynex" branded products are types of allergy and cold medications. But Rynex DM differs from Rynex PE and Rynex PSE in that it's the only one that has a cough suppressant (dextromethorphan).
                  Does Rynex DM contain promethazine or codeine?
                  No. Rynex DM contains brompheniramine (an antihistamine), dextromethorphan (a cough suppressant), and phenylephrine (a decongestant). Similar to promethazine, brompheniramine helps treat allergy symptoms (e.g., itchy eyes, runny nose). And similar to codeine, dextromethorphan helps lower the urge to cough and relieve dry cough.
                  Does Rynex DM cause drowsiness?
                  Yes, it's possible for Rynex DM to cause drowsiness. Rynex DM contains active ingredients that cause drowsiness as a side effect: brompheniramine (an antihistamine) and dextromethorphan (a cough suppressant). But Rynex DM also contains phenylephrine, a decongestant that can have the opposite effect and make you have trouble sleeping. When you first start taking Rynex DM, see how the medication affects your sleep. Contact your primary care provider or pharmacist to discuss better options for you if Rynex DM is making you too sleepy or interrupting your sleep and it's affecting your daily activities.
                  Is Rynex DM over the counter?
                  Yes, Rynex DM is available over the counter without a prescription from a healthcare professional. Ask a pharmacist if you're having trouble finding Rynex DM at your local pharmacy. The pharmacist can recommend other similar medications that you can consider instead.
                  Can I take Rynex DM with acetaminophen (Tylenol)?
                  Possibly. There aren't any known interactions between acetaminophen (Tylenol) and Rynex DM. But keep in mind that acetaminophen (Tylenol) might not be a good choice for everyone, depending on your medical conditions. For example, it's typically not recommended for people with liver problems, unless it's taken as directed by a healthcare professional (HCP). Before you use any over-the-counter pain relievers with Rynex DM, speak with your primary care provider or pharmacist to make sure it's safe for you to do so.
                  Can I take Rynex DM if I'm pregnant or breastfeeding?
                  Don't take Rynex DM if you're pregnant or breastfeeding until you've talked to a healthcare professional first. Rynex DM contains brompheniramine, dextromethorphan, and phenylephrine. Brompheniramine and dextromethorphan are considered safe while pregnant, but it's not completely clear whether phenylephrine is safe for mother and baby during pregnancy. And for when you're breastfeeding, brompheniramine might make your nursing baby sleepy or irritable and phenylephrine might lower your milk supply. Speak with your obstetrician-gynecologist (OB-GYN) if you're pregnant and your baby's primary care provider if you're breastfeeding about the risks and benefits of taking Rynex DM.
                  Is EndaCof-DM the same as Rynex DM?
                  Rynex DM and EndaCof DM are both over-the-counter combination medications. They both contain brompheniramine (an antihistamine), dextromethorphan (a cough suppressant), and phenylephrine (a decongestant). They're both liquids that people 6 years of age and older can take by mouth every 4 hours as needed for certain cold or allergy symptoms. Rynex DM and EndaCof DM are made by different companies under different brand names, and they might differ in flavor.
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                  What are the risks and warnings for Rynex DM?

                  Rynex DM can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                  risk-warning

                  Serotonin syndrome

                  • Risk factors: Taking monoamine oxidase inhibitors (MAOIs) 14 days before starting Rynex DM | Taking other medications that raise serotonin levels in your brain

                    The dextromethorphan in Rynex DM can raise your risk for serotonin syndrome. This is a rare, but potentially life-threatening side effect that happens when there's too much serotonin in the brain. Get medical help right away if you have any symptoms of serotonin syndrome, including fast heart rate, sweating, muscle stiffness or spasms, high fever, and confusion.

                    Your risk for serotonin syndrome is higher if you're also taking other medications that affect serotonin levels, such as certain antidepressants, MAOIs, and certain migraine medications. Make sure your healthcare team knows about all the medications you take or plan to take (including over-the-counter medications and supplements). They can make sure Rynex DM is safe to take with your other medications.

                    risk-warning

                    Accidentally taking too much medication

                    Rynex DM contains an antihistamine (brompheniramine), cough suppressant (dextromethorphan), and a decongestant (phenylephrine). Your risk of accidentally taking too much medication is higher if you use more than one medication with the same or similar ingredients. Antihistamines, dextromethorphan, and decongestants are in many other over-the-counter products. Tell your primary care provider or pharmacist about the medications you take or plan to take to make sure it's safe to take with Rynex DM.

                    Early signs that you might've accidentally taken too much medication include confusion, not being aware of your surroundings, flushed or very warm skin, and vision changes. It could also lead to anxiety or other behavior changes, high blood pressure, and trouble breathing. Get medical help right away or contact a Poison Control Center at 1-800-222-1222 if you think you or a loved one accidentally took too much medication.

                    To prevent accidentally taking too much medication, read the package labels of your medications, review their active ingredient list and age cut-offs, and carefully follow the directions. Don't take more than one medication with an antihistamine, dextromethorphan, or a decongestant on it. Ask a pharmacist if you're not sure whether another product has similar ingredients as Rynex DM.

                    risk-warning

                    Worsening of certain medical conditions

                    • Risk factors: Cough from smoking, asthma, or emphysema | Mucus-producing cough | Breathing problems | Heart disease | High blood pressure | Thyroid problems | High blood sugar (diabetes) | Glaucoma | Urinary problems

                      Let your primary care provider and pharmacist know about all the medical conditions you have before you start taking Rynex DM. Ask them whether this medication is safe for you to take.

                      People who are 65 years of age or older might feel side effects from Rynex DM more intensely. In addition, Rynex DM might worsen certain medical conditions, such as high blood pressure and glaucoma. This medication also might not be appropriate for your condition. For example, you might need other treatment if you have a cough that's lasted for a long time; a cough that occurs with smoking, asthma, or emphysema; or a cough with a lot of mucus.

                      dosage

                      Rynex DM dosage forms

                      The average cost for 118 ml of 2mg/10mg/5mg/10ml of Rynex DM is $4.59 with a free GoodRx coupon. This is 99.6% off the average retail price of $1158.53.
                      ml of oral solution
                      Ml of oral solution
                      DosageQuantityPrice as low asPrice per unit
                      2mg/10mg/5mg/10ml118 ml$4.59$0.04

                      Typical dosing for Rynex DM

                      Note: There are many manufacturers that make this combination medication. They can have different amounts of medication per mL of liquid and slightly different dosages. Check the medication box for the specific instructions for your product.

                      Rynex DM: Each 5 mL contains 1 mg of brompheniramine, 5 mg of dextromethorphan, and 2.5 mg of phenylephrine.

                      • Adults and children age 12 years and older: The typical dose is 20 mL (4 teaspoonfuls) by mouth every 4 hours while you're having symptoms. Don't use more than 6 doses (120 mL) in a 24-hour period.

                      • Children age 6 years to under 12 years: The typical dose is 10 mL (2 teaspoonfuls) by mouth every 4 hours while your child is having symptoms. Don't use more than 6 doses (60 mL) in a 24-hour period.

                      • Children under 6 years old: Ask your child's pediatrician.

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                      How much does Rynex DM cost?

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                      contraindications-icon

                      Rynex DM contraindications

                      Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Rynex DM will not be safe for you to take.
                      alternatives

                      What are alternatives to Rynex DM?

                      There are a number of medications that your doctor can prescribe in place of Rynex DM. Compare a few possible alternatives below.
                      Rynex DM
                      Used for:

                      Short-term relief of symptoms from allergies and the common cold:

                      • Cough from throat and lung irritation

                      • Runny nose

                      • Sneezing

                      • Itchy or watery eyes

                      • Itching of the nose or throat

                      • Stuffy nose (nasal congestion)

                      $3.87 Lowest GoodRx priceView Prices
                      Used for:
                      • Cough

                      • Runny nose

                      • Sneezing

                      • Itchy nose or throat

                      • Itchy or watery eyes

                      • Stuffy nose (nasal congestion)

                      • Sinus congestion

                      $17.85 Lowest GoodRx priceView Prices
                      Used for:
                      • Cough from throat and lung irritation

                      • Runny nose

                      • Sneezing

                      • Itchy or watery eyes

                      • Itching of the nose or throat

                      • Stuffy nose (nasal congestion)

                      $16.72 Lowest GoodRx priceView Prices
                      images

                      Rynex DM images

                      colorless - Rynex DM 1mg-5mg-2.5mg / 5mL Liquid
                      This medicine is Colorless Bottle Of Oral Liquid.colorless - Rynex DM 1mg-5mg-2.5mg / 5mL Liquid

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                      References

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