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Rynex Pse

brompheniramine / pseudoephedrine
Used for Allergic Rhinitis, Cold Symptoms
Used for Allergic Rhinitis, Cold Symptoms

Rynex PSE (brompheniramine / pseudoephedrine) is a combination medication used to treat symptoms from allergies and the common cold. It's available at the pharmacy counter with a valid form of identification.

Reviewed by:
reviewer
Robert Chad Hakim, PharmD, BCCCP
reviewer
Allison Gourley, PharmD
Last reviewed on May 1, 2022
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageCostContraindicationsAlternativesPricesMedicare
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What is Rynex PSE (brompheniramine / pseudoephedrine)?

What is Rynex PSE (brompheniramine / pseudoephedrine) used for?

Short-term relief of symptoms from allergies and the common cold:

  • Runny nose

  • Sneezing

  • Itching of the nose or throat

  • Itchy or watery eyes

  • Nasal and sinus congestion

How Rynex PSE (brompheniramine / pseudoephedrine) works

Rynex PSE (brompheniramine / pseudoephedrine) is a combination of two medications that work together to relieve symptoms caused by allergies and the common cold.

  • Brompheniramine is an antihistamine. It blocks a chemical in your body called histamine. This lowers inflammation in your respiratory tract, which relieves allergy and common cold symptoms like runny or itchy nose and sneezing.

  • Pseudoephedrine is a decongestant that clears your sinuses to relieve sinus pressure.

Are you looking for information on Rynex DM ((brompheniramine / dextromethorphan / phenylephrine), Bromfed DM (brompheniramine / dextromethorphan / pseudoephedrine) or Dimetapp Cold and Allergy (brompheniramine / phenylephrine) instead?

Drug Facts

Common BrandsRynex PSE, Brotapp, Dimetapp
Drug ClassAntihistamine / Decongestant
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityOver-the-counter
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$31.46(save 68.88%)
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$9.79
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What are the side effects of Rynex PSE (brompheniramine / pseudoephedrine)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Other Side Effects

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Excessive sleepiness or dizziness
  • Changes in heartbeat: feeling of racing heartbeats
  • Signs of an overdose: seizures, hallucinations, loss of consciousness, flushed skin, skin that's warm to the touch, vision changes

Source: DailyMed

The following side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Heart palpitations—rapid, pounding, or irregular heartbeat
  • Increase in blood pressure
  • Sudden eye pain or change in vision such as blurry vision, seeing halos around lights, vision loss
  • Trouble passing urine

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

pros-and-cons

Pros and cons of Rynex PSE (brompheniramine / pseudoephedrine)

thumbs-up

Pros

Convenient to take two medications in one liquid

Can treat a wide range of allergy and common cold symptoms

Available over the counter in most states

thumbs-down

Cons

Needs to be taken every 4 to 6 hours

More difficult to customize the dose since it's a fixed-dose combination of two medications

Only available as a liquid

Can't use if you've taken a monoamine oxidate inhibitor (MAOI) in the last 14 days

pharmacist-tips

Pharmacist tips for Rynex PSE (brompheniramine / pseudoephedrine)

pharmacist

  • Rynex PSE (brompheniramine / pseudoephedrine) comes with a medication dosing cup. Be sure to use this cup to measure your dose. Don't use household spoons to measure, because they're not accurate and might cause you to take the wrong dose.

    • Rynex PSE (brompheniramine / pseudoephedrine) can raise your blood pressure. If you have heart problems or high blood pressure, ask your provider if it's safe for you to take Rynex PSE (brompheniramine / pseudoephedrine).

      • Don't use Rynex PSE (brompheniramine / pseudoephedrine) as a way to make a child go to sleep. While Rynex PSE (brompheniramine / pseudoephedrine) usually makes adults sleepy, it can have the opposite effect in children and make them hyper. If your child is having trouble sleeping, contact their provider or pharmacist for other options.

        • Stop using Rynex PSE (brompheniramine / pseudoephedrine) and contact your provider if you get nervous, dizzy, or can't sleep, your symptoms don't get better within 1 week of starting Rynex PSE (brompheniramine / pseudoephedrine), or you develop a fever. These might be signs of another underlying medication condition.

          • Don't start any new medications while taking Rynex PSE (brompheniramine / pseudoephedrine), especially other antihistamines or decongestants, without talking to your provider or pharmacist first. Doing so can raise your risk of overdose and severe side effects, including seizures, hallucinations (seeing things that aren't real), daytime sleepiness, dizziness, high blood pressure, or even death.

            • Tell your provider or pharmacist about all the medications you're taking to make sure Rynex PSE (brompheniramine / pseudoephedrine) is safe for you. Don't take Rynex PSE (brompheniramine / pseudoephedrine) if you're taking or have taken an MAOI, such as selegiline or phenelzine (Nardil), within the past 2 weeks. This combination can cause dangerous changes to your blood pressure. If you've taken an MAOI in the past 2 weeks, contact your provider for other options to treat your symptoms.

              faqs

              Frequently asked questions about Rynex PSE (brompheniramine / pseudoephedrine)

              Can I take Rynex PSE (brompheniramine / pseudoephedrine) if I have other medical conditions?
              Rynex PSE (brompheniramine / pseudoephedrine) might worsen certain medical conditions. This medication might not be appropriate for you if you're 65 years or older or have certain medical conditions, such as glaucoma, breathing problems, and prostate problems. This medication also might not be safe if you're taking certain medications, such as opioids, other antihistamines, and other decongestants. Before taking Rynex PSE (brompheniramine / pseudoephedrine), let your provider know about what other medical conditions you have and ask if this medication is safe for you.
              Can I use Rynex PSE (brompheniramine / pseudoephedrine) only when I need it?
              Yes, you can use Rynex PSE (brompheniramine / pseudoephedrine) as needed. But taking it regularly according to the manufacturer's directions while you're having symptoms might bring you the most relief from your allergy or cold. Use the lowest dose for the shortest amount of time.
              Can I drink alcohol while taking Rynex PSE (brompheniramine / pseudoephedrine)?
              Avoid drinking alcohol while taking Rynex PSE (brompheniramine / pseudoephedrine). Doing so raises your risk of sleepiness and dizziness.
              Can I use Rynex PSE (brompheniramine / pseudoephedrine) if I'm pregnant?
              If you're pregnant or breastfeeding, don't use Rynex PSE (brompheniramine / pseudoephedrine) until you've talked to your provider first to make sure it's safe for you to take.
              Why can't children younger than 6 years old use Rynex PSE (brompheniramine / pseudoephedrine)?
              Children younger than 6 years old can't use Rynex PSE (brompheniramine / pseudoephedrine) because the dosage is too high for them. This raises the risk for overdose and side effects. If your child is having allergy or common cold symptoms, ask your child's provider or pharmacist for other options.
              Where can I find Rynex PSE (brompheniramine / pseudoephedrine) in the pharmacy?
              You can typically find Rynex PSE (brompheniramine / pseudoephedrine) at the pharmacy counter (or behind the counter). You'll be asked to present photo identification and sign when you buy it. This is required because Rynex PSE (brompheniramine / pseudoephedrine) can be used as an ingredient to make the street drug, crystal methamphetamine. Certain states like Oregon consider Rynex PSE (brompheniramine / pseudoephedrine) a controlled substance and put strict regulations on the medication. Ask your pharmacist to help you locate Rynex PSE (brompheniramine / pseudoephedrine) in the pharmacy.
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              What are the risks and warnings for Rynex PSE (brompheniramine / pseudoephedrine)?

              Rynex PSE (brompheniramine / pseudoephedrine) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

              risk-warning

              Sleepiness

              • Risk factors: Drinking alcohol while taking Rynex PSE (brompheniramine / pseudoephedrine) | Taking other medications that cause sleepiness | Age 65 and older

                Rynex PSE (brompheniramine / pseudoephedrine) can make you very sleepy, which can affect your ability to focus, think, or react. This side effect is more likely to happen or be more intense if you're over 65 years old, drink alcohol while taking this medication, or take other medications that cause sleepiness, such as opioids, benzodiazepines, or sleep medications. Don't drive or operate machinery until you know how this medication affects you.

                risk-warning

                Worsening of medical conditions

                • Risk factors: Glaucoma | Heart disease or high blood pressure | Thyroid disease | Diabetes | Breathing problems | Urinary problems

                  Don't take Rynex PSE (brompheniramine / pseudoephedrine) if you have any of the risk factors listed above unless your provider said it's safe to do so. Taking Rynex PSE (brompheniramine / pseudoephedrine) can worsen your condition(s) and cause serious side effects. Make sure your provider knows about all the medical conditions you have or have had in the past before starting Rynex PSE (brompheniramine / pseudoephedrine).

                  risk-warning

                  Accidental overdose

                  Rynex PSE (brompheniramine / pseudoephedrine) contains an antihistamine (brompheniramine) and a decongestant (pseudoephedrine), which are found in many other over-the-counter products. Using more than one medication containing an antihistamine or decongestant, including products used on the skin, can lead to an accidental overdose and cause serious side effects. These effects can include high blood pressure, daytime sleepiness, dizziness, seizures, hallucinations (seeing or hearing things that aren't real), or even death.

                  Tell your provider or pharmacist about the medications you take before starting Rynex PSE (brompheniramine / pseudoephedrine) to make sure it's safe for you. Don't start any new medications while taking Rynex PSE (brompheniramine / pseudoephedrine) without talking to your provider or pharmacist. To prevent an accidental overdose, read package labels carefully. If you're not sure if a product has an antihistamine or a decongestant, ask your pharmacist. If you or your loved one experiences an accidental overdose, get medical help right away or contact a poison control center at 1-800-222-1222.

                  dosage

                  Rynex PSE (brompheniramine / pseudoephedrine) dosage forms

                  The average cost for 1 bottle of 473ml of 1mg/15mg of Rynex PSE (brompheniramine / pseudoephedrine) is $9.79 with a free GoodRx coupon. This is 68.88% off the average retail price of $31.46.
                  bottle of oral solution
                  Bottle of oral solution
                  DosageQuantityPrice as low asPrice per unit
                  473ml of 1mg/15mg1 bottle$9.79$9.79

                  Typical dosing for Rynex PSE (brompheniramine / pseudoephedrine)

                  Each 5 mL of Rynex PSE (brompheniramine / pseudoephedrine) contains 1 mg of brompheniramine and 15 mg of pseudoephedrine.

                  • Adults and children age 12 years or older: The typical dose is 4 teaspoonfuls (20 mL) by mouth every 4 to 6 hours while you're having symptoms. Don't use more than 16 teaspoonfuls (80 mL) in a 24-hour period.

                  • Children 6 to under 12 years of age: The typical dose is 2 teaspoonfuls (10 mL) by mouth every 4 to 6 hours while your child is having symptoms. Don't use more than 8 teaspoonfuls (40 mL) in a 24-hour period.

                  • Children younger than 6 years old: Ask your child's provider.

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                  How much does Rynex PSE (brompheniramine / pseudoephedrine) cost?

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                  contraindications-icon

                  Rynex PSE (brompheniramine / pseudoephedrine) contraindications

                  Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Rynex PSE (brompheniramine / pseudoephedrine) will not be safe for you to take.

                  • Use as a sedative for children

                  • Take an MAOI in the last 14 days

                  alternatives

                  What are alternatives to Rynex PSE (brompheniramine / pseudoephedrine)?

                  There are a number of medications that your doctor can prescribe in place of Rynex PSE (brompheniramine / pseudoephedrine). Compare a few possible alternatives below.
                  Rynex PSE (brompheniramine / pseudoephedrine)
                  Used for:

                  Short-term relief of symptoms from allergies and the common cold:

                  • Runny nose

                  • Sneezing

                  • Itching of the nose or throat

                  • Itchy or watery eyes

                  • Nasal and sinus congestion

                  $9.79 Lowest GoodRx priceView Prices
                  Chlorpheniramine/phenylephrine
                  Used for:

                  • Runny nose

                  • Sneezing

                  • Itchy or watery eyes

                  • Itchy nose or throat

                  • Stuffy nose

                  • Sinus congestion and pressure

                  $18.98 Lowest GoodRx priceView Prices
                  Brompheniramine/phenylephrine
                  Used for:

                  • Nasal congestion

                  • Runny nose

                  • Sneezing

                  • Itching of the nose or throat

                  • Itchy or watery eyes

                  $4.83 Lowest GoodRx priceView Prices

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