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MAOIs

MAOIs are used to treat depression and Parkinson's disease. They work by blocking the enzyme monoamine oxidase (MAO) from breaking down different chemicals, including norepinephrine, serotonin, dopamine. This helps improve mood and control symptoms of Parkinson's disease.

Why are maois prescribed?

  1. Parkinson's Disease (90%)
  2. Depression (10%)

Key takeaways

Monoamine oxidase inhibitors (MAOIs) are used to treat depression and Parkinson's disease. MAOIs work by blocking the enzyme (protein) monoamine oxidase, which breaks down neurotransmitters (chemical messagners) like serotonin, dopamine, and norepinephrine, thereby increasing their levels in the brain. These medications come in different forms, including oral pills and transdermal patches. Examples include selegiline (Emsam), rasagiline (Azilect), and phenelzine (Nardil). These medications have several drug interactions, so talk to your prescriber before starting a new medication if you take an MAOI.

Prices for popular MAOIs medications
Viewing 8 of 8 medications
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selegiline

as low as$29
SELEGILINE treats the symptoms of Parkinson disease in people who are taking Levodopa. It works by increasing the amount of dopamine in your brain, a substance which helps manage body movements and coordination. This reduces the symptoms of Parkinson, such as body stiffness and tremors. It belongs to a group of medications called MAOIs.
RASAGILINE treats the symptoms of Parkinson disease. It works by increasing the amount of dopamine in your brain, a substance which helps manage body movements and coordination. This reduces the symptoms of Parkinson, such as body stiffness and tremors. It belongs to a group of medications called MAOIs.
Nardil (Phenelzine) is a moderately priced monoamine oxidase inhibitor (MAOI). It is used to treat depression in patients who may also have anxiety. This medicine is usually only used when other medicines have not helped. It is less popular than comparable drugs. There is currently no generic alternative to Nardil. The most common version of Nardil is covered by 75% of insurance plans at a co-pay of $60.00-$80.00, however, some pharmacy coupons or cash prices may be lower.
TRANYLCYPROMINE treats depression. It is prescribed when other antidepressant medications have not worked. It works by increasing levels of dopamine, norepinephrine, and serotonin in your brain, substances that help regulate mood. It belongs to a group of medications called MAOIs.
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Marplan

as low as$576
ISOCARBOXAZID treats depression. It works by increasing levels of dopamine, norepinephrine, and serotonin in your brain, substances that help regulate mood. It belongs to a group of medications called MAOIs.
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Xadago

as low as$1,098
Xadago (Safinamide Mesylate) is an expensive monoamine oxidase inhibitor (MAOI). It is used to treat Parkinson's disease. This drug is slightly more popular than comparable drugs. There is currently no generic alternative to Xadago. The most common version of Xadago is covered by 61% of insurance plans at a co-pay of $60.00-$75.00, however, some pharmacy coupons or cash prices may be lower.
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Emsam

as low as$2,163
Emsam (selegiline) is an expensive drug used to treat major depression. This drug is less popular than comparable drugs. There are currently no generic alternatives to Emsam. The most common version of Emsam is covered by 88% of insurance plans at a co-pay of $60.00-$77.50, however, some pharmacy coupons or cash prices may be lower.
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Zelapar

as low as$2,781
SELEGILINE treats the symptoms of Parkinson disease in people who are taking the medication Levodopa. It works by increasing the amount of dopamine in your brain, a substance which helps manage body movements and coordination. This reduces the symptoms of Parkinson, such as body stiffness and tremors. It belongs to a group of medications called MAOIs.
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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