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Antihistamine / Alpha-1 Agonist Combinations

Antihistamine / alpha-1 agonist combinations are used to treat allergic rhinitis, nasal congestion, and cold symptoms. They work by shrinking blood vessels in the nose for congestion and by blocking histamine which causes the symptoms of stuffy nose, runny nose, itchy throat, and sneezing.

Why are antihistamine alpha 1 agonist combinations prescribed?

How are these percentages calculated?

Key takeaways

Antihistamine / alpha-1 agonist combinations are used to treat allergies, cold symptoms, and nasal congestion. These medications work by combining an antihistamine, which blocks the effects of histamine to reduce allergy symptoms, with an alpha-1 agonist, which narrows blood vessels in and around the nose to decrease nasal congestion. You can find these medications in different forms, including oral tablets and syrups. Examples include diphenhydramine / phenylephrine (Benadryl Plus Congestion) and fexofenadine / pseduoephedrine (Allegra-D). These options allow you to choose the form that best fits your needs.

Prices for popular Antihistamine / Alpha-1 Agonist Combinations medications

Viewing 25 of 27 medications

Allegra-D (fexofenadine / pseudoephedrine)

as low as$20

Allegra-D (fexofenadine with pseudoephedrine) is an antihistamine combined with the same active ingredient as Sudafed. It is used to treat seasonal allergies and relieve nasal congestion and sinus pressure. It is sold over the counter, and a generic version is also available.

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Zyrtec-D (cetirizine / pseudoephedrine)

as low as$23

Zyrtec-D (cetirizine with pseudoephedrine) is an antihistamine combined with the same active ingredient as Sudafed. It is used to treat seasonal allergies and relieve nasal congestion and sinus pressure. It is sold over the counter, and a generic version is also available.

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Claritin-D

as low as$45

Claritin-D (loratadine with pseudoephedrine) is used to treat seasonal allergies and relieve nasal congestion and sinus pressure. It is a combination of an antihistamine with the same active ingredient as Sudafed. It works by blocking the action of histamine to relieve allergic symptoms, and by constricting blood vessels in the nose to relieve congestion. It is available over-the-counter and as generic loratadine/pseudoephedrine.

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Aprodine (pseudoephedrine / triprolidine)

as low as$4

PSEUDOEPHEDRINE; TRIPROLIDINE treats the symptoms of the common cold, allergies, or flu. It works by reducing red, itchy eyes and a runny or stuffy nose. It is a combination of an antihistamine and a decongestant.

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ED A-Hist

as low as$4

CHLORPHENIRAMINE; PHENYLEPHRINE treats the symptoms of the common cold, allergies, or flu. It works by reducing red, itchy eyes and a runny or stuffy nose. It is a combination of an antihistamine and a decongestant.

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chlorpheniramine / phenylephrine

as low as$5

CHLORPHENIRAMINE; PHENYLEPHRINE treats the symptoms of the common cold, allergies, or flu. It works by reducing red, itchy eyes and a runny or stuffy nose. It is a combination of an antihistamine and a decongestant.

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Dimetapp (brompheniramine / phenylephrine)

as low as$7

BROMPHENIRAMINE; PHENYLEPHRINE treats the symptoms of the common cold, allergies, or flu. It works by reducing red, itchy eyes and a runny or stuffy nose. It is a combination of an antihistamine and a decongestant.

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chlorpheniramine / pseudoephedrine

as low as$8

Chlorpheniramine/Pseudoephedrine is part of the Antihistamine / Alpha-1 Agonist Combinations class and treats Nasal Congestion and Allergic Rhinitis. Antihistamine / alpha-1 agonist combinations are used to treat allergic rhinitis, nasal congestion, and cold symptoms. They work by shrinking blood vessels in the nose for congestion and by blocking histamine which causes the symptoms of stuffy nose, runny nose, itchy throat, and sneezing. Chlorpheniramine/Pseudoephedrine is only available as a generic drug.

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dexbrompheniramine / phenylephrine

as low as$9

Dexbrompheniramine/Phenylephrine is part of the Antihistamine / Alpha-1 Agonist Combinations class and treats Nasal Congestion. Antihistamine / alpha-1 agonist combinations are used to treat allergic rhinitis, nasal congestion, and cold symptoms. They work by shrinking blood vessels in the nose for congestion and by blocking histamine which causes the symptoms of stuffy nose, runny nose, itchy throat, and sneezing. Dexbrompheniramine/Phenylephrine is only available as a generic drug.

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Rymed

as low as$9

Rymed is part of the Antihistamine / Alpha-1 Agonist Combinations class and treats Allergic Rhinitis. Antihistamine / alpha-1 agonist combinations are used to treat allergic rhinitis, nasal congestion, and cold symptoms. They work by shrinking blood vessels in the nose for congestion and by blocking histamine which causes the symptoms of stuffy nose, runny nose, itchy throat, and sneezing. Rymed is only available as a brand name drug.

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Rynex Pse

as low as$10

BROMPHENIRAMINE; PSEUDOEPHEDRINE is a combination of an antihistamine and a decongestant. It is used to treat the symptoms of allergy and colds. This medicine will not treat an infection.\n \nThis medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

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Benadryl Plus Congestion (diphenhydramine / phenylephrine)

as low as$10

Benadryl Plus Congestion is part of the Antihistamine / Alpha-1 Agonist Combinations class and treats Nasal Congestion. Antihistamine / alpha-1 agonist combinations are used to treat allergic rhinitis, nasal congestion, and cold symptoms. They work by shrinking blood vessels in the nose for congestion and by blocking histamine which causes the symptoms of stuffy nose, runny nose, itchy throat, and sneezing. Benadryl Plus Congestion is only available as a brand name drug.

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Ninjacof-D

as low as$13

Ninjacof-D is only available as a brand name drug.

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Alahist D

as low as$16

Alahist D is only available as a brand name drug.

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Alahist PE

as low as$17

Alahist PE is only available as a brand name drug.

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Ru-Hist D

as low as$18

BROMPHENIRAMINE; PHENYLEPHRINE treats the symptoms of the common cold, allergies, or flu. It works by reducing red, itchy eyes and a runny or stuffy nose. It is a combination of an antihistamine and a decongestant.

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Nohist LQ

as low as$19

CHLORPHENIRAMINE; PHENYLEPHRINE treats the symptoms of the common cold, allergies, or flu. It works by reducing red, itchy eyes and a runny or stuffy nose. It is a combination of an antihistamine and a decongestant.

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Stahist AD

as low as$21

Stahist AD is part of the Antihistamine / Alpha-1 Agonist Combinations class and treats Allergic Rhinitis. Antihistamine / alpha-1 agonist combinations are used to treat allergic rhinitis, nasal congestion, and cold symptoms. They work by shrinking blood vessels in the nose for congestion and by blocking histamine which causes the symptoms of stuffy nose, runny nose, itchy throat, and sneezing. Stahist AD is only available as a brand name drug.

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Poly Hist Forte

as low as$24

Poly Hist Forte is part of the Antihistamine / Alpha-1 Agonist Combinations class and treats Nasal Congestion and Allergic Rhinitis. Antihistamine / alpha-1 agonist combinations are used to treat allergic rhinitis, nasal congestion, and cold symptoms. They work by shrinking blood vessels in the nose for congestion and by blocking histamine which causes the symptoms of stuffy nose, runny nose, itchy throat, and sneezing. Poly Hist Forte is only available as a brand name drug.

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chlophedianol / dexchlorpheniramine / pseudoephedrine

as low as$25

CHLOPHEDIANOL; DEXCHLORPHENIRAMINE; PSEUDOEPHEDRINE treats the symptoms of the common cold, allergies, or flu. It works by reducing red, itchy eyes and cough. It also decreases a runny or stuffy nose. It is a combination of an antihistamine, a cough suppressant, and a decongestant.

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rondec-d

as low as$27

Rondec-D is part of the Antihistamine / Alpha-1 Agonist Combinations class and treats Nasal Congestion and Allergic Rhinitis. Antihistamine / alpha-1 agonist combinations are used to treat allergic rhinitis, nasal congestion, and cold symptoms. They work by shrinking blood vessels in the nose for congestion and by blocking histamine which causes the symptoms of stuffy nose, runny nose, itchy throat, and sneezing. Rondec-D is only available as a generic drug.

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promethazine VC

as low as$29

PROMETHAZINE; PHENYLEPHRINE treats the symptoms of the common cold, allergies, or flu. It works by reducing red, itchy eyes and a runny or stuffy nose. It is a combination of an antihistamine and a decongestant.

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lohist d

as low as$32

Lohist D is part of the Antihistamine / Alpha-1 Agonist Combinations class and treats Nasal Congestion and Allergic Rhinitis. Antihistamine / alpha-1 agonist combinations are used to treat allergic rhinitis, nasal congestion, and cold symptoms. They work by shrinking blood vessels in the nose for congestion and by blocking histamine which causes the symptoms of stuffy nose, runny nose, itchy throat, and sneezing. Lohist D is only available as a generic drug.

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Rescon

as low as$36

Rescon is only available as a brand name drug.

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Lodrane D

as low as$61

BROMPHENIRAMINE; PSEUDOEPHEDRINE treats the symptoms of the common cold, allergies, or flu. It works by reducing red, itchy eyes and a runny or stuffy nose. It is a combination of an antihistamine and a decongestant.

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Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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