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Fexofenadine / Pseudoephedrine Coupon - Fexofenadine / Pseudoephedrine 12 hour tablet

fexofenadine / pseudoephedrine

Generic Allegra-D
Used for Nasal Congestion, Allergic Rhinitis
Used for Nasal Congestion, Allergic Rhinitis

Allegra-D is a combination of two medications: pseudoephedrine (a decongestant) and fexofenadine (an antihistamine). It's taken by people ages 12 years and older to relieve allergy symptoms, like sinus congestion and runny nose. Allegra-D (fexofenadine / pseudoephedrine) is taken by mouth, either every 12 hours or every 24 hours, depending on the formulation (Allegra-D 12-hour or Allegra-D 24-hour. Some common side effects include headache and trouble sleeping. This medication is available as both brand name and generics.

Reviewed by:
reviewer
Robert Chad Hakim, PharmD, BCCCP
reviewer
Allison Gourley, PharmD
Last reviewed on October 22, 2024
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostContraindicationsAlternativesLatest newsImagesReferencesPricesMedicare
basics-icon

What is Allegra-D (fexofenadine / pseudoephedrine)?

What is Allegra-D (fexofenadine / pseudoephedrine) used for?

Short-term relief of allergy symptoms in adults and children ages 12 years and older:

  • Itchy nose or throat

  • Sneezing

  • Itchy or watery eyes

  • Runny or stuffy nose

  • Sinus congestion or pressure

How Allegra-D (fexofenadine / pseudoephedrine) works

Allegra-D (fexofenadine / pseudoephedrine) is a combination of two medications that work together to relieve allergy symptoms.

Are you looking for information on Allegra (fexofenadine) instead?
When does Allegra-D (fexofenadine / pseudoephedrine) start working?
Time passed since treatment started:
MINUTES
HOURS
DAYS
WEEKS
MONTHS
Initial effect
Full effect

Drug Facts

Common BrandsAllegra-D
Drug ClassAntihistamine / Decongestant
Controlled Substance ClassificationControlled in some states. See FAQs below.
Generic StatusLower-cost generic available
AvailabilityOver-the-counter
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$52.490
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$52.49
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What are the side effects of Allegra-D (fexofenadine / pseudoephedrine)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Other Side Effects

  • Dry mouth
  • Dizziness
  • Nervousness

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
When do Allegra-D (fexofenadine / pseudoephedrine) possible side effects begin and end?
Time passed since treatment started:
MINUTES
HOURS
DAYS
WEEKS
MONTHS
Headache
Trouble sleeping
Nausea

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

Trouble in sleeping

Less common

Cough

dizziness

irregular heartbeat

nervousness

sore throat

Incidence not known

Difficult or labored breathing

difficulty swallowing

dizziness

fast heartbeat

feeling of warmth

fever

hives or welts

itching skin

itching, puffiness or swelling of the eyelids or around the eyes, face, lips or tongue

large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs

reddening of the skin, especially around ears

redness of the face, neck, arms and occasionally, upper chest

shortness of breath

skin rash

tightness in chest

swelling of eyes, face, or inside of nose

unusual tiredness or weakness

wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Headache

nausea

Less common

Abdominal or stomach pain

agitation

anxiety

back pain

dry mouth

heartburn

Incidence not known

Terrifying dreams causing sleep disturbances

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Allegra-D (fexofenadine / pseudoephedrine)

thumbs-up

Pros

Starts working within an hour

Easier to take a combination pill instead of two separate pills

Available as a once-daily tablet

Available over the counter (behind the counter)

thumbs-down

Cons

Tablets can't be crushed or chewed and there isn't a liquid version available

Best to take on empty stomach

Not for children younger than 12 years old

Not a good option for people with kidney or heart problems

pharmacist-tips

Pharmacist tips for Allegra-D (fexofenadine / pseudoephedrine)

pharmacist

  • Swallow Allegra-D (fexofenadine / pseudoephedrine) tablets whole. Don't cut, crush, or chew the tablets. This will affect the way the medication works since it's made to release the medication into your body slowly over time.

    • Take Allegra-D (fexofenadine / pseudoephedrine) with a glass of water on an empty stomach. Don't take it with fruit juices because they might affect how well Allegra-D (fexofenadine / pseudoephedrine) gets absorbed into your body.

      • You might experience trouble sleeping (insomnia) after starting Allegra-D (fexofenadine / pseudoephedrine). To prevent this medication from affecting your sleep, it's best not to take your dose too close to bedtime.

        • Both fexofenadine and pseudophedrine interact with other medications, such as other cold and allergy medications, or blood pressure medications. Ask your healthcare team or pharmacist to help you check for medication interactions when you're taking Allegra-D (fexofenadine / pseudoephedrine).

          • Avoid taking Allegra-D (fexofenadine / pseudoephedrine) and antacids containing aluminum or magnesium (e.g., Mylanta, Rolaids) within a few hours of each other. Taking these medications too close together can potentially cause the fexofenadine in Allegra-D to not work as well to treat your allergies.

            • Stop taking Allegra-D (fexofenadine / pseudoephedrine) and contact your primary care provider if your allergy symptoms don't get better within 7 days of starting Allegra-D (fexofenadine / pseudoephedrine) or if you develop a fever. These might be signs of a serious condition that needs more medical attention.

              • Store Allegra-D (fexofenadine / pseudoephedrine) up and away from children and pets. That way, they're less likely to reach it and accidentally take the medication. If you think your child accidentally took the medication, call a Poison Control Center right away at 1-800-222-1222.

                faqs

                Frequently asked questions about Allegra-D (fexofenadine / pseudoephedrine)

                Is Allegra-D (fexofenadine / pseudoephedrine) a decongestant?
                Yes, pseudoephedrine in Allegra-D is a decongestant that's used to treat nasal and sinus congestion.
                What's the difference between Allegra and Allegra-D?
                Both Allegra-D and Allegra contain the antihistamine fexofenadine to help treat symptoms like runny nose, itchy or watery eyes, and sneezing. But Allegra-D also contains the decongestant pseudoephedrine, which is why the letter "D" is in the brand name, Allegra-D. If you're experiencing nasal or sinus congestion and pressure in addition to other typical allergy symptoms, Allegra-D is a better choice than Allegra.
                How long does Allegra-D (fexofenadine / pseudoephedrine) take to work?
                Allegra-D (fexofenadine / pseudoephedrine) starts to treat allergy symptoms within an hour after taking a dose. The effects of the medication last for 12 hours (for the 12-hour tablet) or 24 hours (for the 24-hour tablet).
                How many days in a row can you take Allegra-D (fexofenadine / pseudoephedrine)?
                Ask your healthcare team how long you can take Allegra-D (fexofenadine / pseudoephedrine). The manufacturer doesn't set a time limit on how long you can take this medication. But they recommend that you contact your primary care provider if your allergy symptoms haven't improved after taking this medication for a week, or if you develop a fever because these might be signs that you need more medical attention. In addition, because the pseudoephedrine in Allegra-D can affect your blood pressure and heart rate, your healthcare team might recommend a different option for you if you need to take an allergy medication long-term.
                Can Allegra-D (fexofenadine / pseudoephedrine) cause anxiety?
                Yes, the pseudoephedrine in Allegra-D might cause you to feel anxious. This side effect is temporary and should go away after the medication wears off. Let your primary care provider know if Allegra-D (fexofenadine / pseudoephedrine) is making you feel too anxious to go about your day or if this side effect doesn't get better with time. They might ask you to take a lower dose or recommend that you take a different medication.
                Can Allegra-D (fexofenadine / pseudoephedrine) raise blood pressure?
                Yes, pseudoephedrine in Allegra-D can raise your blood pressure. If you already have high blood pressure, check with your primary care provider to see if you can take Allegra-D (fexofenadine / pseudoephedrine). They might recommend a different medication for you if they don't think this medication is a safe option.
                Can you take Allegra-D (fexofenadine / pseudoephedrine) while pregnant?
                If you're pregnant or thinking of getting pregnant, don't take Allegra-D (fexofenadine / pseudoephedrine) until you've talked with your obstetrician-gynecologist (OB-GYN) first. Allegra-D contains pseudoephedrine and research is mixed on whether it's safe to take during pregnancy. Your OB-GYN might recommend that you avoid using Allegra-D (fexofenadine / pseudoephedrine) at least during the first 3 months of pregnancy because of the potential risk of harm to babies. If you experience allergy symptoms during pregnancy, talk with your healthcare team about safer options.
                Is Allegra-D (fexofenadine / pseudoephedrine) over the counter?
                Yes, Allegra-D (fexofenadine / pseudoephedrine) is an over-the-counter medication that you can find at local pharmacies. But you can only purchase it at the pharmacy counter (or behind the counter) with a valid photo identification and signature. There are strict regulations around this medication because it contains pseudoephedrine, which can potentially be misused. Some states consider Allegra-D (fexofenadine / pseudoephedrine) a controlled substance. Ask your pharmacist if you have questions about how to purchase Allegra-D (fexofenadine / pseudoephedrine) in the pharmacy.
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                What are the risks and warnings for Allegra-D (fexofenadine / pseudoephedrine)?

                Allegra-D (fexofenadine / pseudoephedrine) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                risk-warning

                Fast heart rate and high blood pressure

                • Risk factors: Heart problems | High blood pressure

                  Pseudoephedrine in Allegra-D can raise your heart rate and blood pressure, even at recommended doses. If you have a history of heart problems or high blood pressure, ask your cardiologist if Allegra-D (fexofenadine / pseudoephedrine) is safe for you before taking this medication. If you get severe headaches, nosebleeds, difficulty breathing, irregular heartbeat, or chest pain while taking Allegra-D (fexofenadine / pseudoephedrine), stop taking it and get medical attention right away. These can be signs of seriously high blood pressure.

                  risk-warning

                  Worsening of certain medical conditions

                  • Risk factors: Heart problem | High blood pressure | Thyroid problem | High blood sugar (diabetes) | Glaucoma | Breathing problem (e.g., emphysema, long-term bronchitis) | Kidney problems | Urinary condition

                    Talk with your primary care provider or pharmacist first before you start Allegra-D (fexofenadine / pseudoephedrine) if you have other medical conditions. They can make sure this medication is safe and appropriate for you to take.

                    People who are 65 years of age or older might feel side effects from Allegra-D (fexofenadine / pseudoephedrine) more intensely. In addition, this medication might worsen certain medical conditions, like high blood pressure, thyroid problems, diabetes, glaucoma, and breathing problems.

                    risk-warning

                    Accidentally taking too much medication

                    Allegra-D contains an antihistamine (fexofenadine) and a decongestant (pseudoephedrine). Antihistamines and decongestants are commonly found in other over-the-counter and prescription medications.

                    Taking too many antihistamines or too many decongestants can be dangerous and lead to serious side effects, including high blood pressure, seizures, and hallucinations (seeing or hearing things that aren't real).

                    Ask your primary care provider or pharmacist if you're not sure whether you're taking a medication that has the same or similar ingredients as Allegra-D. Tell your primary care provider or pharmacist about the medications you take or plan to take to make sure they're safe for you. Get medical help or contact a Poison Control Center at 1-800-222-1222 right away if you think you or a loved one accidentally took too much medication.

                    dosage

                    Allegra-D (fexofenadine / pseudoephedrine) dosage forms

                    The average cost for 60 tablets of 12 hour of Allegra-D (fexofenadine / pseudoephedrine) is $68.25 with a free GoodRx coupon. This is -4.34% off the average retail price of $65.41.
                    tablet
                    Tablet
                    DosageQuantityPrice as low asPrice per unit
                    12 hour60 tablets$68.25$1.14
                    24 hour30 tablets$55.34$1.84

                    Typical dosing for Allegra-D (fexofenadine / pseudoephedrine)

                    Allegra-D (fexofenadine / pseudoephedrine) 24-hour tablet:
                    Each tablet contains 180 mg of fexofenadine and 240 mg of pseudoephedrine.

                    • People ages 12 to under 65 years old: The typical dose is 1 tablet by mouth once a day on an empty stomach. Don't take more than 1 tablet in 24 hours.

                    • People ages 65 years and older: Ask your primary care provider.

                    Allegra-D (fexofenadine / pseudoephedrine) 12-hour tablet:
                    Each tablet contains 60 mg of fexofenadine and 120 mg of pseudoephedrine.

                    • People ages 12 to under 65 years old: The typical dose is 1 tablet by mouth every 12 hours on an empty stomach. Don't take more than 2 tablets in 24 hours.

                    • People ages 65 years and older: Ask your primary care provider.

                    Your dose might be different if you have kidney problems.

                    interactions

                    Interactions between Allegra-D (fexofenadine / pseudoephedrine) and other drugs

                    Allegra-D (fexofenadine / pseudoephedrine) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Allegra-D (fexofenadine / pseudoephedrine). Please note that only the generic name of each medication is listed below.

                    Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                    Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                    Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                    • Aluminum Carbonate, Basic
                    • Aluminum Hydroxide
                    • Aluminum Phosphate
                    • Dihydroxyaluminum Aminoacetate
                    • Dihydroxyaluminum Sodium Carbonate
                    • Magaldrate
                    • Magnesium Carbonate
                    • Magnesium Hydroxide
                    • Magnesium Oxide
                    • Magnesium Trisilicate
                    • St John's Wort
                    drug-cost

                    How much does Allegra-D (fexofenadine / pseudoephedrine) cost?

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                    contraindications-icon

                    Allegra-D (fexofenadine / pseudoephedrine) contraindications

                    Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Allegra-D (fexofenadine / pseudoephedrine) will not be safe for you to take.
                    alternatives

                    What are alternatives to Allegra-D (fexofenadine / pseudoephedrine)?

                    There are a number of medications that your doctor can prescribe in place of Allegra-D (fexofenadine / pseudoephedrine). Compare a few possible alternatives below.
                    Allegra-D (fexofenadine / pseudoephedrine)
                    Used for:

                    Short-term relief of allergy symptoms in adults and children ages 12 years and older:

                    • Itchy nose or throat

                    • Sneezing

                    • Itchy or watery eyes

                    • Runny or stuffy nose

                    • Sinus congestion or pressure

                    $52.49 Lowest GoodRx priceView Prices
                    Claritin-D (loratadine / pseudoephedrine)
                    Used for:

                    • Runny nose

                    • Itchy nose or throat

                    • Itchy or watery eyes

                    • Stuffy nose

                    • Nasal congestion

                    • Sinus congestion or pressure

                    $13.61 Lowest GoodRx priceView Prices
                    Zyrtec-D (cetirizine / pseudoephedrine)
                    Used for:

                    • Itchy nose or throat

                    • Sneezing

                    • Itchy or watery eyes

                    • Runny or stuffy nose

                    • Sinus congestion or pressure

                    $26.05 Lowest GoodRx priceView Prices
                    latest news

                    What is the latest news about Allegra-D (fexofenadine / pseudoephedrine)?

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                    images

                    Allegra-D (fexofenadine / pseudoephedrine) images

                    White And Tan W07 - Fexofenadine Hydrochloride / Pseudoephedrine Hydrochloride 60mg-120mg 12 Hour Extended-Release Tablet
                    This medicine is White And Tan Tablet Imprinted With "W07".White And Tan W07 - Fexofenadine Hydrochloride / Pseudoephedrine Hydrochloride 60mg-120mg 12 Hour Extended-Release Tablet
                    White And Yellow Oval 724 - CVS Allergy Relief D 12 Hour 60mg-120mg Extended-Release Tablet
                    This medicine is White And Yellow, Oval Tablet Imprinted With "724".White And Yellow Oval 724 - CVS Allergy Relief D 12 Hour 60mg-120mg Extended-Release Tablet

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                    References

                    Best studies we found

                    Cardinal Health. (2024). Fexofenadine HCl and pseudoephedrine HCl 24 hour- fexofenadine hcl and pseudoephedrine hcl tablet, extended release [package insert]. DailyMed.

                    CVS Pharmacy. (2024). Fexofenadine hydrochloride and pseudoephedrine hydrochloride tablet, extended release [package insert]. DailyMed.

                    North, M. L., et al. (2013). Double blind randomized crossover trial of PF-03654764 + fexofenadine in the environmental exposure unit (EEU). Allergy, Asthma & Clinical Immunology.

                    View All References (2)

                    Sussman, G. L., et al. (1999). The efficacy and safety of fexofenadine HCl and pseudoephedrine, alone and in combination, in seasonal allergic rhinitis. The Journal of Allergy and Clinical Immunology.

                    U.S. Food and Drug Administration. (2024). Legal requirements for the sale and purchase of drug products containing pseudoephedrine, ephedrine, and phenylpropanolamine.

                    GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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