Lohist D is part of the Antihistamine / Alpha-1 Agonist Combinations class and treats Nasal Congestion and Allergic Rhinitis. Antihistamine / alpha-1 agonist combinations are used to treat allergic rhinitis, nasal congestion, and cold symptoms. They work by shrinking blood vessels in the nose for congestion and by blocking histamine which causes the symptoms of stuffy nose, runny nose, itchy throat, and sneezing. Lohist D is only available as a generic drug. Get Lohist D for as low as $23.59, which is 60% off the average retail price of $59.24 for the most common version, by using a GoodRx coupon.