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Stahist AD

chlorcyclizine / pseudoephedrine
Used for Allergic Rhinitis
Used for Allergic Rhinitis

Stahist AD (chlorcyclizine / pseudoephedrine) is a combination of two medications: chlorcyclizine (an antihistamine) and pseudoephedrine (a decongestant). It's used to relieve symptoms of the common cold, hay fever (seasonal allergies), and other respiratory allergies in adults and children. Stahist AD (chlorcyclizine / pseudoephedrine) might cause certain side effects, such as sleepiness, nervousness, and dry mouth. Typically, you don't need a prescription to buy Stahist AD (chlorcyclizine / pseudoephedrine). But you can only purchase it with valid form of identification at the pharmacy counter because pseudoephedrine is a restricted medication.

Reviewed by:
reviewer
Robert Chad Hakim, PharmD, BCCCP
reviewer
Kristianne Hannemann, PharmD
Last reviewed on April 7, 2024
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageCostContraindicationsAlternativesReferencesPricesMedicare
basics-icon

What is Stahist AD (chlorcyclizine / pseudoephedrine)?

What is Stahist AD (chlorcyclizine / pseudoephedrine) used for?

Short-term relief of symptoms of the common cold, hay fever, or other upper respiratory allergies:

  • Runny nose

  • Sneezing

  • Itching of the nose or throat

  • Itchy or watery eyes

  • Stuffy nose (nasal congestion)

How Stahist AD (chlorcyclizine / pseudoephedrine) works

Stahist AD (chlorcyclizine / pseudoephedrine) is a combination of two medications.

  • Chlorcyclizine is first-generation antihistamine that blocks a chemical called histamine, which is responsible for sneezing, itching, and other allergy symptoms.

  • Pseudoephedrine is a decongestant that tightens the blood vessels in your nose to help with swelling and pressure. This will allow you to breathe better.

Are you looking for information on Ahist (chlorcyclizine) instead?

Drug Facts

Common BrandsStahist AD
Drug ClassAntihistamine / Decongestant
Controlled Substance ClassificationControlled in some states. See FAQs below.
Generic StatusNo lower-cost generic available
AvailabilityOver-the-counter
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What are the side effects of Stahist AD (chlorcyclizine / pseudoephedrine)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Other Side Effects

  • Constipation
  • Difficulty urinating
  • Blurry vision
  • Excitability (hyperactivity), especially in children
  • Trouble sleeping

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • High blood pressure or fast heart rate: chest pain, blurry vision, headache, fatigue

Source: DailyMed

pros-and-cons

Pros and cons of Stahist AD (chlorcyclizine / pseudoephedrine)

thumbs-up

Pros

Can relieve a wide variety of common cold or allergy symptoms

More convenient to take two medications in a single dose

Might not cause as much drowsiness as diphenhydramine (Benadryl)

Typically available without a prescription

thumbs-down

Cons

Might need to take as often as every 6 hours to relieve symptoms

More difficult to customize the dose since it's a fixed combination of two medications

Not the best choice for people with certain medical conditions (e.g., glaucoma, high blood pressure, trouble urinating)

Only available as a tablet

pharmacist-tips

Pharmacist tips for Stahist AD (chlorcyclizine / pseudoephedrine)

pharmacist

  • You can take Stahist AD (chlorcyclizine / pseudoephedrine) with or without food. If it upsets your stomach, try taking the medication with food.

    • If Stahist AD (chlorcyclizine / pseudoephedrine) is making you sleepy or dizzy during the day, it can affect your ability to focus, think, or react. Don't drive until you know how this medication affects you. Also, avoid alcohol while taking this medication because it can make sleepiness worse.

      • While Stahist AD (chlorcyclizine / pseudoephedrine) can make adults sleepy, it's possible for children who use this medication to become overly excited or energetic. If this happens to your child, speak to your child's pediatrician.

        • Don't start any new medications while taking Stahist AD (chlorcyclizine / pseudoephedrine), particularly other medications containing other antihistamines or decongestants (phenylephrine or pseudoephedrine), without talking to your primary care provider or pharmacist first. Doing so can raise your risk of overdose and severe side effects.

          • Don't take Stahist AD (chlorcyclizine / pseudoephedrine) with a monoamine oxidase inhibitor (MAOI), such as selegiline or phenelzine (Nardil). This combination can raise your risk for severe side effects (e.g., serotonin syndrome, dizziness). If you're currently taking or have taken an MAOI in the last 2 weeks, don't use Stahist AD (chlorcyclizine / pseudoephedrine). Contact your primary care provider for other options to treat your cold or allergy symptoms.

            • Stop using Stahist AD (chlorcyclizine / pseudoephedrine) and contact your primary care provider if your cold or allergy symptoms last longer than 1 week, keep coming back, or new symptoms appear. These might be signs of a more serious condition that needs more medical attention.

              • If you're pregnant or breastfeeding, don't take Stahist AD (chlorcyclizine / pseudoephedrine) until you've talked to a healthcare professional first. There's limited information on how safe it is to take pseudoephedrine during pregnancy. And there's a risk that taking pseudoephedrine during nursing can dry up breast milk supply.

                faqs

                Frequently asked questions about Stahist AD (chlorcyclizine / pseudoephedrine)

                How long does it take Stahist AD (chlorcyclizine / pseudoephedrine) to work?
                Both chlorcyclizine and pseudoephedrine, the active ingredients in Stahist AD (chlorcyclizine / pseudoephedrine), typically start to work within 40 minutes. The effects of the medication is expected to last for about 6 to 8 hours.
                How often can you take Stahist AD (chlorcyclizine / pseudoephedrine)?
                Adults and children ages 6 years and older can take Stahist AD (chlorcyclizine / pseudoephedrine) as often as every 6 hours, up to 3 doses within a 24-hour period. If your healthcare professional (HCP) specifically recommended you to take Stahist AD (chlorcyclizine / pseudoephedrine), it's possible they might give you different instructions than what's written on the manufacturer's box; follow your HCP's directions in that case. Ask your HCP or pharmacist if you're not sure how much Stahist AD (chlorcyclizine / pseudoephedrine) you can take and how often you should take the medication.
                Is Stahist AD (chlorcyclizine / pseudoephedrine) a steroid?
                No, Stahist AD (chlorcyclizine / pseudoephedrine) doesn't contain a steroid. This medication contains an antihistamine (chlorcyclizine) that treats certain allergy symptoms like runny nose, sneezing, itchy nose and throat, and watery eyes. It also contains a decongestant (pseudoephedrine) that treats nasal and sinus congestion. If your allergy symptoms aren't getting better with Stahist AD (chlorcyclizine / pseudoephedrine) alone, you can consider trying a nasal steroid spray or contact your primary care provider for guidance.
                Can you buy Stahist AD (chlorcyclizine / pseudoephedrine) over the counter?
                You can find Stahist AD (chlorcyclizine / pseudoephedrine) behind the counter at the pharmacy. While you typically don't need a prescription to purchase this medication, states do put strict regulations around it. This is because Stahist AD contains pseudoephedrine, a medication that has the potential to be misused. You'll need to show photo identification and provide your signature when you buy the medication. Ask your pharmacist if you're not sure where you can find Stahist AD (chlorcyclizine / pseudoephedrine) in the pharmacy.
                Does Stahist AD (chlorcyclizine / pseudoephedrine) cause drowsiness?
                Yes, it's possible to feel drowsy after you take Stahist AD (chlorcyclizine / pseudoephedrine) because it contains chlorcyclizine, an antihistamine. But, research suggests people experience drowsiness less often with chlorcyclizine than with diphenhydramine (Benadryl), another first-generation antihistamine. Additionally, Stahist AD (chlorcyclizine / pseudoephedrine) also contains pseudoephedrine, which can have the opposite effect and make you stay awake. Pay attention to how Stahist AD (chlorcyclizine / pseudoephedrine) affects your sleep. Contact your primary care provider to discuss better options for you if it's making you too sleepy or interrupting your sleep and affecting your daily activities.
                Can you take Stahist AD (chlorcyclizine / pseudoephedrine) with acetaminophen (Tylenol)?
                Stahist AD (chlorcyclizine / pseudoephedrine) isn't known to have a direct interaction with acetaminophen (Tylenol). But if you have liver problems, ask your primary care provider first if it's safe for you to take acetaminophen (Tylenol) because it can be harmful to the liver. Your care team can let you know if it's appropriate for you to take Stahist AD (chlorcyclizine / pseudoephedrine) with acetaminophen (Tylenol).
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                What are the risks and warnings for Stahist AD (chlorcyclizine / pseudoephedrine)?

                Stahist AD (chlorcyclizine / pseudoephedrine) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                risk-warning

                Worsening of medical conditions

                • Risk factors: Breathing problems (e.g., emphysema, long-term bronchitis) | Glaucoma | Urinary problems | Heart problems | High blood pressure | Thyroid problems | Diabetes

                  Don't take Stahist AD (chlorcyclizine / pseudoephedrine) if you have any of the risk factors listed above unless your primary care provider (PCP) said it's safe to do so. Taking this medication can worsen your condition(s) and cause serious side effects. Make sure your PCP knows about all medical conditions you have or have had in the past before starting Stahist AD (chlorcyclizine / pseudoephedrine).

                  risk-warning

                  Accidental overdose

                  Stahist AD (chlorcyclizine / pseudoephedrine) contains an antihistamine (chlorcyclizine), and a decongestant (pseudoephedrine), which can be found in many other over-the-counter products. Using more than one medication containing an antihistamine or decongestant can lead to an accidental overdose and cause serious side effects. These serious side effects include seizures, hallucinations, fainting, confusion, flushed skin, skin that's warm to the touch, vision changes, or even death.

                  To prevent an accidental overdose, read package labels carefully. If you're not sure if a product has any similar ingredients, ask your pharmacist. If you or your loved one experiences an accidental overdose, get medical help as soon as possible or contact a poison control center at 1-800-222-1222.

                  dosage

                  Stahist AD (chlorcyclizine / pseudoephedrine) dosage forms

                  The average cost for 30 tablets of 25mg/60mg of Stahist AD (chlorcyclizine / pseudoephedrine) is $21.14 with a free GoodRx coupon. This is 15.97% off the average retail price of $25.15.
                  tablet
                  Tablet
                  DosageQuantityPrice as low asPrice per unit
                  25mg/60mg30 tablets$21.14$0.70

                  Typical dosing for Stahist AD (chlorcyclizine / pseudoephedrine)

                  Each tablet contains 25 mg of chlorcyclizine and 60 mg of pseudoephedrine.

                  • Age 12 years and older: The typical dose is 1 tablet by mouth every 6 to 8 hours. The maximum dose is 3 tablets (3 doses) in 24 hours, or as directed by a healthcare professional.

                  • Age 6 years to under 12 years: The typical dose is half a tablet by mouth every 6 to 8 hours. The maximum dose is one and a half tablets (3 doses) in 24 hours, or as directed by a healthcare professional.

                  • Age under 6 years: Ask your child's pediatrician.

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                  How much does Stahist AD (chlorcyclizine / pseudoephedrine) cost?

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                  Stahist AD (brand)
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                  contraindications-icon

                  Stahist AD (chlorcyclizine / pseudoephedrine) contraindications

                  Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Stahist AD (chlorcyclizine / pseudoephedrine) will not be safe for you to take.

                  • Currently taking or have taken an MAOI in the last 14 days

                  alternatives

                  What are alternatives to Stahist AD (chlorcyclizine / pseudoephedrine)?

                  There are a number of medications that your doctor can prescribe in place of Stahist AD (chlorcyclizine / pseudoephedrine). Compare a few possible alternatives below.
                  Stahist AD (chlorcyclizine / pseudoephedrine)
                  Used for:

                  Short-term relief of symptoms of the common cold, hay fever, or other upper respiratory allergies:

                  • Runny nose

                  • Sneezing

                  • Itching of the nose or throat

                  • Itchy or watery eyes

                  • Stuffy nose (nasal congestion)

                  $21.14 Lowest GoodRx priceView Prices
                  Zyrtec-D (cetirizine / pseudoephedrine)
                  Used for:

                  • Itchy nose or throat

                  • Sneezing

                  • Itchy or watery eyes

                  • Runny or stuffy nose

                  • Sinus congestion or pressure

                  $26.05 Lowest GoodRx priceView Prices
                  Claritin-D (loratadine / pseudoephedrine)
                  Used for:

                  • Runny nose

                  • Itchy nose or throat

                  • Itchy or watery eyes

                  • Stuffy nose

                  • Nasal congestion

                  • Sinus congestion or pressure

                  $13.61 Lowest GoodRx priceView Prices

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                  References

                  Best studies we found

                  GÅ‚owacka, K., et al. (2021). Pseudoephedrine-benefits and risks. International Journal of Molecular Sciences.

                  Jenkins, C. M., et al. (1950). A clinical study of chlorcyclizine hydrochloride, ‘Perazil’; A new antihistaminic drug. Journal of the National Medical Association.

                  Magna Pharmaceuticals, Inc. (2023). Stahist AD- chlorcyclizine hydrochloride and pseudoephedrine hydrochloride tablet [package insert]. DailyMed.

                  View All References (3)

                  PubChem. (n.d.). Chlorcyclizine. National Library of Medicine.

                  Simons, F. E., et al. (2008). H1 antihistamines: Current status and future directions. The World Allergy Organization Journal.

                  U.S. Food and Drug Administration. (2024). Legal requirements for the sale and purchase of drug products containing pseudoephedrine, ephedrine, and phenylpropanolamine.

                  GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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