Alpha-1 agonists are used to treat conditions like nasal congestion and low blood pressure. They also have other uses, such as managing facial redness and eye redness. These medications work by stimulating alpha-1 receptors, which cause blood vessels to constrict. This leads to increased blood pressure and reduced swelling. Alpha-1 agonists come in different forms, including oral pills, eye drops, and nasal sprays. Examples include pseudoephedrine (Sudafed), phenylephrine (Sudafed PE), and oxymetazoline (Afrin). You can choose the form that best fits your needs.