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Steglatro vs. Jardiance

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Steglatro (ertugliflozin) and Jardiance (empagliflozin) are both medications in the sodium-glucose cotransporter 2 (SGLT2) inhibitor class used to treat Type 2 diabetes. They help lower blood sugar by preventing sugar from being reabsorbed into the body through the kidneys, causing it to be removed in the urine. While both medications are taken orally once a day, they have some differences. Steglatro is only approved for Type 2 diabetes, whereas Jardiance is also approved to reduce the risk of heart-related complications and worsening kidney problems in certain adults. Jardiance can be used in people as young as 10 years old, while Steglatro is for adults only. The typical starting dose for Steglatro is 5 mg, which can be increased to 15 mg, while Jardiance starts at 10 mg and can be increased to 25 mg. Both medications can cause urinary tract infections, yeast infections, and increased urination. Neither medication is currently available as a lower-cost generic.

Steglatro

(ertugliflozin)

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Jardiance

(empagliflozin)

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Summary for Steglatro

Prescription only

Steglatro (ertugliflozin) is an oral medication that helps lower blood sugar in adults with Type 2 diabetes. It belongs to the drug class called sodium glucose cotransporter 2 (SGLT2) inhibitors. Steglatro (ertugliflozin) is a tablet you take once a day. But it works best when you also follow a balanced diet and regular exercise plan. Common side effects include yeast infections and urinary tract infections. Currently, Steglatro (ertugliflozin) is a brand-name medication only; there's no generic version yet.

Indications for Steglatro

Pros and Cons for Steglatro

Pros

  • Only need to take once a day
  • Can take with or without meals

Cons

  • Might raise the risk of yeast infections
  • Not recommended for people with Type 1 diabetes or those with severe kidney problems

Common Side Effects for Steglatro

  • Yeast infections in females (9-12%)
  • Yeast infections in males (4%)
  • Urinary tract infections (4%)
  • Headache (3-4%)

Warnings for Steglatro

  • Ketoacidosis
  • Low fluids in the body (leading to risk of low blood pressure or sudden kidney problems)
  • Serious genital infections and urinary tract infections
  • Leg and foot amputations
  • Low blood sugar when taken with certain diabetes medications

Summary for Jardiance

Prescription only

Jardiance (empagliflozin) is a medication that helps lower blood sugar for people 10 years and older with Type 2 diabetes. For the best results, it's used along with a nutritious diet and exercise. Jardiance (empagliflozin) can also help lower the risk of complications, hospital stays, and death for adults with heart failure or chronic kidney disease (CKD). This medication belongs to the drug class called sodium-glucose cotransporter 2 (SGLT2) inhibitors. It comes as a tablet that you take by mouth once a day. Side effects include urinary tract infections (UTIs) and yeast infections.

Indications for Jardiance

  • Type 2 diabetes (in addition to diet and exercise) in people age 10 years and older
  • Lowering the risk of death due to heart problems in adults with Type 2 diabetes and heart disease
  • Lowering the risk of hospital stays and death due to heart problems in adults with heart failure
  • Lowering the risk of worsening kidney problems, hospital stays, and death due to heart problems in adults with chronic kidney disease (CKD)

Pros and Cons for Jardiance

Pros

  • Taken by mouth once a day
  • Might notice some weight loss
  • Can take with other diabetes medications

Cons

Common Side Effects for Jardiance

Warnings for Jardiance

  • Ketoacidosis
  • Low fluids in the body (leading to low blood pressure or dehydration)
  • Genital and urinary tract infections
  • Low blood sugar (hypoglycemia) when used with certain other diabetes medications
  • Leg and foot amputations
  • Allergic reactions

Prices with our coupons for Steglatro vs. Jardiance

Price Card Drug Icon
Steglatro30 tablets / 15mg
$350.19$428.50
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Jardiance30 tablets / 10mg
$350.61$809.93
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