Key takeaways
Prezista (darunavir) and Prezcobix (darunavir/cobicistat) are both medications used to treat HIV infections, but they have some key differences. Prezista is taken with a booster like ritonavir (Norvir) to help it work better, while Prezcobix already includes a booster, cobicistat, in the same pill. This makes Prezcobix more convenient since it combines two medications into one tablet. Prezista can be used in children as young as 3 years old, whereas Prezcobix is only for people weighing at least 88 pounds. Prezista is available as both a tablet and an oral suspension, which can be helpful if you have trouble swallowing pills, but Prezcobix is only available as a tablet. Both medications need to be taken with food and can cause similar side effects like rash and liver problems. However, Prezcobix is not recommended during pregnancy, while Prezista can be used safely during pregnancy.
